2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-, 3,4-dihydro-5-methoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-7-yl ester manufacturers
- AChE-IN-19
-
- $2500.00
-
2026-04-21
- CAS:2742707-36-2
- Purity:
- Supply Ability: 10g
|
| | 2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-, 3,4-dihydro-5-methoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-7-yl ester Basic information |
| Product Name: | 2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-, 3,4-dihydro-5-methoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-7-yl ester | | Synonyms: | 2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-, 3,4-dihydro-5-methoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-7-yl ester;AChE-IN-19 | | CAS: | 2742707-36-2 | | MF: | C30H33NO7 | | MW: | 519.59 | | EINECS: | | | Product Categories: | | | Mol File: | 2742707-36-2.mol | ![2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-, 3,4-dihydro-5-methoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-7-yl ester Structure](CAS/20210305/GIF/2742707-36-2.gif) |
| | 2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-, 3,4-dihydro-5-methoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-7-yl ester Chemical Properties |
| Boiling point | 682.2±55.0 °C(Predicted) | | density | 1.202±0.06 g/cm3(Predicted) | | pka | 2.95±0.12(Predicted) |
| | 2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-, 3,4-dihydro-5-methoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-7-yl ester Usage And Synthesis |
| Uses | AChE-IN-19 (compound A15) is a highly potent AChE inhibitor with an IC50 value of 0.56 μM, also inhibits Aβ aggregation. AChE-IN-19 has potent neuroprotective activities and nearly no toxicity on SH-SY5Y cells. AChE-IN-19 can be used for researching Alzheimer's disease[1]. | | IC 50 | AChE | | References | [1] Shi S, et al. Semi-synthesis and biological evaluation of flavone hybrids as multifunctional agents for the potential treatment of Alzheimer's disease. Bioorg Chem. 2020 Jul;100:103917. DOI:10.1016/j.bioorg.2020.103917 |
| | 2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-, 3,4-dihydro-5-methoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-7-yl ester Preparation Products And Raw materials |
|