3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide

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3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide Suppliers list
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Email: klq@cw-bio.com
Company Name: Jinan Jiuli Biotechnology Co. , Ltd.  
Tel: 15865264761
Email: 486064515@qq.com
Company Name: TargetMol Chemicals Inc.  
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Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide manufacturers
3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide Basic information
Product Name:3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide
Synonyms:3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide;Antitumor agent-70
CAS:2454133-88-9
MF:C21H18N4O2
MW:358.39
EINECS:
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Mol File:2454133-88-9.mol
3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide Structure
3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide Chemical Properties
density 1.20±0.1 g/cm3(Predicted)
pka11.07±0.46(Predicted)
Safety Information
MSDS Information
3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide Usage And Synthesis
UsesAntitumor agent-70 (compound 8b) has anti-tumor activity and can induce cell apoptosis. Antitumor agent-70 inhibits multiple myeloma with an IC50 value of 0.12 μM. Antitumor agent-70 is a potential multi-targeted kinase inhibitor especially for c-Kit[1].
References[1] Xin-Yang Li, et al. Design, synthesis and biological evaluation of novel (E)-N-phenyl-4-(pyridine-acylhydrazone) benzamide derivatives as potential antitumor agents for the treatment of multiple myeloma (MM). Bioorg Chem. 2020 Oct;103:104189. DOI:10.1016/j.bioorg.2020.104189
3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide Preparation Products And Raw materials
Tag:3-Pyridinecarboxylic acid, (2E)-2-[[4-[[(4-methylphenyl)amino]carbonyl]phenyl]methylene]hydrazide(2454133-88-9) Related Product Information
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