Rimonabant hydrochloride manufacturers
- Rimonabant HCl
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- $20.00 / 1kg
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2024-01-08
- CAS:158681-13-1
- Min. Order: 1kg
- Purity: 99.60%
- Supply Ability: 50tons
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| | Rimonabant hydrochloride Basic information |
| | Rimonabant hydrochloride Chemical Properties |
| Melting point | 230-240°C | | storage temp. | 2-8°C | | solubility | DMSO: soluble20mg/mL, clear | | form | powder | | color | white to beige | | InChI | 1S/C22H21Cl3N4O.ClH/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15;/h5-10,13H,2-4,11-12H2,1H3,(H,27,30);1H | | InChIKey | REOYOKXLUFHOBV-UHFFFAOYSA-N | | SMILES | CC1=C(C2=CC=C(Cl)C=C2)N(C3=CC=C(Cl)C=C3Cl)N=C1C(NN4CCCCC4)=O.Cl | | CAS DataBase Reference | 158681-13-1(CAS DataBase Reference) |
| Hazard Codes | T,Xi | | Risk Statements | 25-36 | | Safety Statements | 26-45 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral
Eye Irrit. 2 |
| | Rimonabant hydrochloride Usage And Synthesis |
| Chemical Properties | White to Off-White Crystalline Solid | | Uses | The first of a new class of selective (Cannabinoid-1 (CB-1) receptor antagonists | | Uses | A brain cannabinoid receptor (CB1) antagonist. Antiobesity agent. | | Uses | Rimonabant hydrochloride has been used as an antagonist of cannabinoid 1 (CB1) receptor:
- to study its effects on protein synthesis in C2C12 myotubes
- to analyze its effects on human astroglia
- in combination with methanandamide (mAEA) to study its effects on murine gastric vagal afferent mechanosensitivity
| | Hazard | A poison. | | Biochem/physiol Actions | Rimonabant acts as a mycobacterial membrane protein large 3 (MMPL3) inhibitor. Rimonabant hydrochloride exhibits therapeutic activity against weight reduction and smoking cessation. | | storage | Desiccate at RT |
| | Rimonabant hydrochloride Preparation Products And Raw materials |
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