| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:TNIK-IN-6
CAS:2375196-40-8
Package:5mg;50mg
|
| Company Name: |
Changzhou Yourui Pharmaceutical Technology Co., Ltd
|
| Tel: |
18168818882 |
| Email: |
877458914@qq.com |
| Products Intro: |
Product Name:5-Bromo-2-(2-fluoro-4-pyridinyl)-1,7-naphthyridin-8-amine
CAS:2375196-40-8
Purity:98% Package:100mg;1g;10g;50g;100g;500g;1kg;10kg
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5-Bromo-2-(2-fluoro-4-pyridinyl)-1,7-naphthyridin-8-amine manufacturers
- TNIK-IN-6
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2026-07-27
- CAS:2375196-40-8
- Purity:
- Supply Ability: 10g
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| | 5-Bromo-2-(2-fluoro-4-pyridinyl)-1,7-naphthyridin-8-amine Basic information |
| | 5-Bromo-2-(2-fluoro-4-pyridinyl)-1,7-naphthyridin-8-amine Chemical Properties |
| Boiling point | 484.6±40.0 °C(Predicted) | | density | 1.669±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | pka | 3.08±0.30(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | 5-Bromo-2-(2-fluoro-4-pyridinyl)-1,7-naphthyridin-8-amine Usage And Synthesis |
| Uses | TNIK-IN-6 (Compound 9) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK) and , with IC50 of 0.93 μM, that plays important roles in neurological and psychiatric disorders[1][2]. | | References | [1] Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73. DOI:10.1016/j.bmcl.2012.11.013
[2] Jon Read, et al. Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase. Bioorg Med Chem Lett. 2019 Aug 1;29(15):1962-1967. DOI:10.1016/j.bmcl.2019.05.032 |
| | 5-Bromo-2-(2-fluoro-4-pyridinyl)-1,7-naphthyridin-8-amine Preparation Products And Raw materials |
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