- Isorhapontigenin
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- $39.00
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2026-05-26
- CAS:32507-66-7
- Purity: 99.40%
- Supply Ability: 10g
- Isorhapontigenin
-
-
2026-05-22
- CAS:32507-66-7
- Min. Order: 1kg
- Purity: >98%
- Supply Ability: 1000 kg
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| | isorhapontigenin Basic information |
| Product Name: | isorhapontigenin | | Synonyms: | isorhapontigenin;(E)-3,4',5-Trihydroxy-3'-methoxystilbene;(E)-3'-Methoxystilbene-3,4',5-triol;(E)-3-Methoxy-stilbene-4,3',5'-triol;5-[(E)-2-(4-Hydroxy-3-methoxyphenyl)ethenyl]-1,3-benzenediol;100MG/1G/100G;3,4',5-Trihydroxy-3'-methoxy-trans-stilbene;(E)-3'-Methoxy-3,4',5-stilbenetriol | | CAS: | 32507-66-7 | | MF: | C15H14O4 | | MW: | 258.27 | | EINECS: | 803-480-7 | | Product Categories: | | | Mol File: | 32507-66-7.mol |  |
| | isorhapontigenin Chemical Properties |
| Melting point | 180.0 to 184.0 °C | | Boiling point | 471.8±35.0 °C(Predicted) | | density | 1.345 | | storage temp. | room temp | | solubility | DMSO: soluble15mg/mL, clear | | pka | 9.16±0.10(Predicted) | | form | powder | | color | white to light brown | | InChI | InChI=1S/C15H14O4/c1-19-15-8-10(4-5-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+ | | InChIKey | ANNNBEZJTNCXHY-NSCUHMNNSA-N | | SMILES | C1(O)=CC(/C=C/C2=CC=C(O)C(OC)=C2)=CC(O)=C1 |
| Hazard Codes | Xi | | Risk Statements | 37/38-41-43-51 | | Safety Statements | 26-36/37/39 | | WGK Germany | 3 | | HS Code | 2909.50.5000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Dam. 1
Skin Irrit. 2
STOT SE 3 |
| | isorhapontigenin Usage And Synthesis |
| Chemical Properties | White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Belamcanda chinensis. | | Uses | Isorhapontigenin, an orally bioavailable dietary polyphenol isolated from the Chinese herb Gnetum cleistostachyum, displays anti-inflammatory effects. Isorhapontigenin induces autophagy and inhibits invasive bladder cancer formation[1][2]. | | Definition | ChEBI: Isorhapontigenin is a stilbenoid. | | Biochem/physiol Actions | Isorhapontigenin or 4-methoxyresveratrol is a stilbene derivative isolated from a number of plants including Chinese medical herbs Gnetum Cleistostachyum and Iris Domestica (Belamcanda chinensis, leopard lily), and wine grapes. Similarly to resveratrol, isorhapontigenin is a potent antioxidant that attenuates ROS generation. Also, Isorhapontigenin exhibits pro-apoptopic and anti-cancer activities through downregulation of XIAP (X-linked inhibitor of apoptosis protein). | | References | [1] Yeo SCM, et al. Isorhapontigenin, a bioavailable dietary polyphenol, suppresses airway epithelial cell inflammation through a corticosteroid-independent mechanism. Br J Pharmacol. 2017 Jul;174(13):2043-2059. DOI:10.1111/bph.13803
[2] Liang Y, et al. SESN2/sestrin 2 induction-mediated autophagy and inhibitory effect of isorhapontigenin (ISO) on human bladder cancers. Autophagy. 2016 Aug 2;12(8):1229-39. DOI:10.1080/15548627.2016.1179403
[3] Jiang G, et al. Isorhapontigenin (ISO) Inhibits Invasive Bladder Cancer Formation In Vivo and Human Bladder Cancer Invasion In Vitro by Targeting STAT1/FOXO1 Axis. Cancer Prev Res (Phila). 2016 Jul;9(7):567-80. DOI:10.1158/1940-6207.CAPR-15-0338 |
| | isorhapontigenin Preparation Products And Raw materials |
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