| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:SM1044
CAS:1331880-08-0
Package:10mg;50mg
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| Product Name: | SM1044 | | Synonyms: | SM1044;Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]-N-[2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]ethyl]- | | CAS: | 1331880-08-0 | | MF: | C34H55NO10 | | MW: | 637.8 | | EINECS: | | | Product Categories: | | | Mol File: | 1331880-08-0.mol |  |
| | SM1044 Chemical Properties |
| Boiling point | 658.822±55.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.252±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 8.032±0.19(predicted) |
| | SM1044 Usage And Synthesis |
| Uses | SM1044 is a dihydroartemisinin (DHA) dimer. SM1044 activates caspase, induces apooptosis in RL95-2 and KLE cells. SM1044 inhibits proliferations of cancer cells RL95-2, KLE, HEC-50, HEC-1-A, HEC-1-B, AN3CA, with IC50 < 3.6 μM . SM1044 inhbits tumor growth in RL95-2 xenograft mouse model[1]. | | References | [1] Zhu Y, et al., Novel dihydroartemisinin dimer containing nitrogen atoms inhibits growth of endometrial cancer cells and may correlate with increasing intracellular peroxynitrite. Sci Rep. 2019 Oct 29;9(1):15528. DOI:10.1038/s41598-019-52108-6 |
| | SM1044 Preparation Products And Raw materials |
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