Tubulin polymerization-IN-57

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Tubulin polymerization-IN-57 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Tubulin polymerization-IN-57 Basic information
Product Name:Tubulin polymerization-IN-57
Synonyms:Tubulin polymerization-IN-57;Carbamic acid, N-[6-(1-naphthalenyloxy)-1H-benzimidazol-2-yl]-, methyl ester
CAS:95385-38-9
MF:C19H15N3O3
MW:333.34
EINECS:
Product Categories:
Mol File:95385-38-9.mol
Tubulin polymerization-IN-57 Structure
Tubulin polymerization-IN-57 Chemical Properties
density 1.393±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka7.354±0.46(predicted)
Safety Information
MSDS Information
Tubulin polymerization-IN-57 Usage And Synthesis
UsesTubulin polymerization-IN-57 (compound 5a) is a tubulin inhibitor and is an α-naphthoxy-substituted carbendazim (HY-13582) derivative. Tubulin polymerization-IN-57 induces mitotic arrest and inhibits cancer cell proliferation[1].
References[1] Cano-González L et al. Structure-Based Optimization of Carbendazim-Derived Tubulin Polymerization Inhibitors through Alchemical Free Energy Calculations. J Chem Inf Model. 2023 Nov 27;63(22):7228-7238. DOI:10.1021/acs.jcim.3c01379
Tubulin polymerization-IN-57 Preparation Products And Raw materials
Tag:Tubulin polymerization-IN-57(95385-38-9) Related Product Information
Carbamic acid, [5-(2-propenyloxy)-1H-benzimidazol-2-yl]-, methyl ester (9CI) Oxibendazole ethyl N-[5-(propan-2-yloxy)-1H-1,3-benzodiazol-2-yl]carbamate methyl 5-hydroxy-2-benzimidazole carbamate ethyl N-[5-(2-methylpropoxy)-1H-1,3-benzodiazol-2-yl]carbamate ethyl N-(5-methoxy-1H-1,3-benzodiazol-2-yl)carbamate