(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol

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(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Email: info@tianfuchem.com
Products Intro: Product Name:(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
CAS:289893-25-0
Purity:99% Package:25KG;5KG;1KG
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Arimoclomol
CAS:289893-25-0
Purity:99.81% Package:1mg;117USD|5mg;262USD|10mg;388USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: RongNa Biotechnology Co.,Ltd
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Email: Brad@rongnabiotech.com
Products Intro: Product Name:(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
CAS:289893-25-0
Purity:0.99
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:Amrioclomol
CAS:289893-25-0
Purity:95% Remarks:Please reach out to us for more information about custom solutions.
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:Arimoclomol
CAS:289893-25-0
Purity:99.81% Package:1mg;117USD|5mg;262USD|10mg;388USD

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol manufacturers

  • Arimoclomol
  • Arimoclomol pictures
  • $54.00
  • 2026-04-22
  • CAS:289893-25-0
  • Purity: 99.81%
  • Supply Ability: 10g
  • Arimoclomol
  • Arimoclomol pictures
  • $54.00
  • 2026-04-22
  • CAS:289893-25-0
  • Purity: 99.81%
  • Supply Ability: 10g
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Basic information
Product Name:(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
Synonyms:(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol;Amrioclomol;(2R-)Arimoclomol NEW;BRX-220 free base;3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide;aggregation,Heat shock proteins,HSP,co-inducer,system,BRX220,motor,Arimoclomol,inhibit,ubiquitin,BRX 220,neurons,misfolded,proteasome,BRX-220,protein,assemblies,clearance,Inhibitor;Arimoclomol, 10 mM in DMSO;(2R-)Arimoclomol
CAS:289893-25-0
MF:C14H20ClN3O3
MW:313.78
EINECS:
Product Categories:
Mol File:289893-25-0.mol
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Structure
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Chemical Properties
Melting point 93 - 95o C
Boiling point 539.2±60.0 °C(Predicted)
density 1.32±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka14.03±0.20(Predicted)
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Usage And Synthesis
UsesArimoclomol is a co-inducer of HSP that acts through heat shock factor 1 (HSF1) in cells undergoing cellular stress. Has therapeutic potential in motor neuron degenerative diseases. Potential treatment for liposomal storage disorders, such as Niemann-Pick disease type C.
in vivo

Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect against cholecystokinin-octapeptide (CCK)-induced acute pancreatitis[1].

Animal Model:Male Wistar rats weighing 240 to 270 g[1]
Dosage:20 mg/kg
Administration:Administered intragastrically, for 5 days
Result:Had a protective effect against CCK-induced acute pancreatitis.
IC 50HSP
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Preparation Products And Raw materials
Tag:(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol(289893-25-0) Related Product Information
Aprepitant