3,4-Diphenyl-5H-furan-2-one

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Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
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3,4-Diphenyl-5H-furan-2-one manufacturers

3,4-Diphenyl-5H-furan-2-one Basic information
Product Name:3,4-Diphenyl-5H-furan-2-one
Synonyms:3,4-diphenyl-2H-furan-5-one;2(5H)-Furanone, 3,4-diphenyl-;3,4-Diphenyl-2,5-Dihydrofuran-2-One;3,4-Diphenyl-5H-furan-2-one, 10 mM in DMSO
CAS:5635-16-5
MF:C16H12O2
MW:236.27
EINECS:
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Mol File:5635-16-5.mol
3,4-Diphenyl-5H-furan-2-one Structure
3,4-Diphenyl-5H-furan-2-one Chemical Properties
Safety Information
MSDS Information
3,4-Diphenyl-5H-furan-2-one Usage And Synthesis
Uses3,4-Diphenyl-5H-furan-2-one is a natural compound isolated from the endophytic fungus Aspergillus flavipes AIL8 derived from the mangrove plant Acanthus ilicifolius. 3,4-Diphenyl-5H-furan-2-one is a derivative of 2,3-diphenyltetrahydrofuran (DPTF), which is a COX-2 inhibitor. 3,4-Diphenyl-5H-furan-2-one can be used as a lead compound for inflammation and pain[1][2].
References[1] Bai Z Q, et al. New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius[J]. Fitoterapia, 2014, 95: 194-202. DOI:10.1016/j.fitote.2014.03.021
[2] Singh P, et al. 2, 3-Diphenyltetrahydrofurans (DPTF)-A new class of stereogenic diarylheterocycles as potential COX-2 inhibitors-Computational evaluation of COX-2-DPTF binding behaviour[J]. 2006.
3,4-Diphenyl-5H-furan-2-one Preparation Products And Raw materials
Tag:3,4-Diphenyl-5H-furan-2-one(5635-16-5) Related Product Information
2,3-Diphenylmaleic anhydride Phenylmaleic anhydride 2(5H)-Furanone,4-phenyl- 2(5H)-Furanone, 4-(4-methylphenyl)- 2,5-Furandione, 3-(4-methylphenyl)- 4-(5-Oxo-2,5-dihydrofuran-3-yl)benzonitrile