NSC-124854

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NSC-124854 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
NSC-124854 Basic information
Product Name:NSC-124854
Synonyms:NSC-124854;2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-5-O-phosphonopentofuranosyl)-5,6-dihydro-6-iodo-
CAS:1033942-30-1
MF:C9H15IN3O7P
MW:435.11
EINECS:
Product Categories:
Mol File:1033942-30-1.mol
NSC-124854 Structure
NSC-124854 Chemical Properties
Boiling point 669.594±65.00 °C(Press: 760.00 Torr)(predicted)
density 2.555±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka1.856±0.10(predicted)
Safety Information
MSDS Information
NSC-124854 Usage And Synthesis
UsesNSC-124854 is a DNA polymerase β (Pol-β) inhibitor with an IC50 of 5.3 μM. NSC-124854 has antitumor activity[1].
References[1] Jaiswal AS, et al. DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer. PLoS One. 2011 Feb 2;6(2):e16691. DOI:10.1371/journal.pone.0016691
NSC-124854 Preparation Products And Raw materials
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