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| Product Name: | KUNG65 | | Synonyms: | KUNG65;Benzoic acid, 3-chloro-2-[2-[2-[(4-fluorophenyl)methyl]phenyl]ethyl]-4,6-dihydroxy-, methyl ester | | CAS: | 2144469-30-5 | | MF: | C23H20ClFO4 | | MW: | 414.85 | | EINECS: | | | Product Categories: | | | Mol File: | 2144469-30-5.mol |  |
| | KUNG65 Chemical Properties |
| Boiling point | 564.927±29.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.324±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 6.744±0.28(predicted) |
| | KUNG65 Usage And Synthesis |
| Uses | KUNG65 is a selective inhibitor of Grp94, with a target Kd of 540 nM and at least 73 fold selectivity vs. the other Hsp90 isoforms[1]. | | References | [1] Kyler Pugh, et al. Investigation of the site 2 pocket of Grp94 with KUNG65 benzamide derivatives. Bioorg Med Chem Lett. 2024 Oct 1:111:129893. DOI:10.1016/j.bmcl.2024.129893 |
| | KUNG65 Preparation Products And Raw materials |
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