PFI-7

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PFI-7 Suppliers list
Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Email: xuexiang.shao@tsbiochem.com
PFI-7 Basic information
Product Name:PFI-7
Synonyms:PFI-7;Acetamide, N-[cis-4-(1H-benzimidazol-2-yl)cyclohexyl]-2-[(1H-indol-2-ylmethyl)amino]-
CAS:2910938-58-6
MF:C24H27N5O
MW:401.5
EINECS:
Product Categories:
Mol File:2910938-58-6.mol
PFI-7 Structure
PFI-7 Chemical Properties
Boiling point 757.770±60.00 °C(Press: 760.00 Torr)(predicted)
density 1.293±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka11.806±0.10(predicted)
Safety Information
MSDS Information
PFI-7 Usage And Synthesis
UsesPFI-7 is a probe, which binds to human GID4 (KD is 79 nM), and antagonizes the binding of Pro/N-degrons. PFI-7 can be utilized in C-terminal to LisH (CTLH) complex research and development of targeted protein degradation[1].
References[1] Owens DDG, et al., A chemical probe to modulate human GID4 Pro/N-degron interactions. Nat Chem Biol. 2024 May 21. DOI:10.1038/s41589-024-01618-0
PFI-7 Preparation Products And Raw materials
Tag:PFI-7(2910938-58-6) Related Product Information
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