- azido-PEG8-OH
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2025-06-07
- CAS:352439-36-2
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | alpha-Azido-omega-hydroxy octa(ethylene glycol) Basic information |
| | alpha-Azido-omega-hydroxy octa(ethylene glycol) Chemical Properties |
| storage temp. | 2-8°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | form | Liquid | | color | Colorless to light yellow | | α-end | azide | | Ω-end | hydroxyl | | BRN | 8940056 | | InChI | 1S/C16H33N3O8/c17-19-18-1-3-21-5-7-23-9-11-25-13-15-27-16-14-26-12-10-24-8-6-22-4-2-20/h20H,1-16H2 | | InChIKey | BUMODEBRFGPXRM-UHFFFAOYSA-N | | SMILES | OCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | HS Code | 2929900090 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | alpha-Azido-omega-hydroxy octa(ethylene glycol) Usage And Synthesis |
| Description | Azide-PEG8-alcohol is a click chemistry reagent with an azide(N3) and a terminal hydroxyl group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl (OH) group enables further derivatization or replacement with other functional groups. | | Uses | O-(2-Azidoethyl)heptaethylene glycol is used to synthesize oligo and poly(ethylene glycol) derivatives that are used as structural units of dendrimers, hydrogels, surface modifiers, self-assembling systems and molecular crosslinkers. This precursor is compatible for acetylene-azide click reactions.
Some of the reported applications include:
- Synthesis of strain-stiffening hydrogels through self-assembly of oligomers fibres derived from Azido-PEG (n=7).
- Synthesis of biodegradable tetra-PEG hydrogels for drug delivery system.
- Synthesis of heterobifunctional oligo(ethylene glycol) linkers for bioconjugation and targeted drug delivery.
- Preparation of synthetic amphiphiles for programmed pH-dependent dispersions of carbon nanotubes (CNTs).
- Selective glycoprotein detection through allosteric click-imprinting by using a self-assembled monolayer developed from the above oligomer.
- Preparation of bioactivated quantum dot micelles containing fluorescent nanocrystals.
| | reaction suitability | reaction type: click chemistry
reagent type: cross-linking reagent | | IC 50 | PEGs |
| | alpha-Azido-omega-hydroxy octa(ethylene glycol) Preparation Products And Raw materials |
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