(E)-3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one

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(E)-3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one manufacturers

  • MAO-B-IN-19
  • MAO-B-IN-19 pictures
  • 2026-05-12
  • CAS:152897-41-1
  • Purity:
  • Supply Ability: 10g
(E)-3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one Basic information
Product Name:(E)-3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one
Synonyms:(E)-3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one;2-Propen-1-one, 3-(4-fluorophenyl)-1-(2-hydroxyphenyl)-, (2E)-;MAO-B-IN-19
CAS:152897-41-1
MF:C15H11FO2
MW:242.24
EINECS:
Product Categories:
Mol File:152897-41-1.mol
(E)-3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one Structure
(E)-3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one Chemical Properties
Melting point 117-118 °C(Solv: ethanol (64-17-5))
Boiling point 394.8±42.0 °C(Predicted)
density 1.258±0.06 g/cm3(Predicted)
pka7.79±0.30(Predicted)
Safety Information
HS Code 2914310000
MSDS Information
(E)-3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one Usage And Synthesis
UsesMAO-B-IN-19 is a selective MAO-B inhibitor with an IC50of0.67μM. MAO-B-IN-19 shows neuroprotective and anti-inflammatory properties[1].
IC 50MAO-B: 0.67 μM (IC50)
References[1] Rui Chen, et al. Development of the "hidden" multi-target-directed ligands by AChE/BuChE for the treatment of Alzheimer's disease. Eur J Med Chem. 2023 May 5;251:115253. DOI:10.1016/j.ejmech.2023.115253
(E)-3-(4-fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one Preparation Products And Raw materials
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