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| | H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Basic information |
| Product Name: | H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) | | Synonyms: | CRUSTACEAN CARDIOACTIVE PEPTIDE, CCAP;H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9);PRO-PHE-CYS-ASN-ALA-PHE-THR-GLY-CYS(DISULFIDE BRIDGE CYS3-CYS9);L-Cysteine, L-prolyl-L-phenylalanyl-L-cysteinyl-L-asparaginyl-L-alanyl-L-phenylalanyl-L-threonylglycyl-;Crustacean cardioactive peptide, free acid;Crustacean Cardioactive Peptide , CCAPfreeacid | | CAS: | 309247-84-5 | | MF: | C42H58N10O12S2 | | MW: | 959.1 | | EINECS: | | | Product Categories: | Peptide | | Mol File: | 309247-84-5.mol |  |
| | H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO : 50 mg/mL (52.13 mM);Water : < 0.1 mg/mL (insoluble) | | form | Solid | | color | White to off-white |
| | H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Usage And Synthesis |
| Uses | Crustacean cardioactive peptide, free acid is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean cardioactive peptide, free acid also modulates the neuronal activity in other arthropods. | | in vivo | CCAP, FMRFamide and SALDKNFMRFamide increase the mosquito antennal accessory pulsatile organ (APO) and heart contraction rates, increase hemolymph flow velocity in the antennal space[1]. | | References | [1] Suggs JM, et al. CCAP and FMRFamide-like peptides accelerate the contraction rate of the antennal accessory pulsatile organs (auxiliary hearts) of mosquitoes. J Exp Biol. 2016 Aug 1;219(Pt 15):2388-95. DOI:10.1242/jeb.141655
[2] Moris-Sanz M, et al. The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B. Biol Open. 2015 Aug 14;4(9):1132-42. DOI:10.1242/bio.012872 |
| | H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Preparation Products And Raw materials |
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