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| | H-Gly-Arg-pNA Basic information |
| Product Name: | H-Gly-Arg-pNA | | Synonyms: | H-Gly-Arg-pNA;Glycine-L-Argininep-nitroanilide dihydrochloride≥ 98% (HPLC);GR-PNA;L-Argininamide, glycyl-N-(4-nitrophenyl)-;Gly-Arg-pNA | | CAS: | 103192-40-1 | | MF: | C14H21N7O4 | | MW: | 351.36 | | EINECS: | | | Product Categories: | | | Mol File: | 103192-40-1.mol |  |
| | H-Gly-Arg-pNA Chemical Properties |
| density | 1.50±0.1 g/cm3(Predicted) | | pka | 12.48±0.70(Predicted) | | Sequence | Gly-{Arg-pNA} |
| | H-Gly-Arg-pNA Usage And Synthesis |
| Chemical Properties | Light yellow powder | | Uses | Gly-Arg-pNA is a fluorogenic substrate for the measurement of protease activity. Gly-Arg-pNA undergoes hydrolysis and releases the fluorescent product p-nitroaniline. p-nitroaniline is in a fluorescent state under ultraviolet light irradiation and can emit a fluorescent signal [1][2]. | | References | [1] Hutchinson DW, et, al. The preparation and properties of immobilised dipeptidyl-aminopeptidase I (cathepsin C). Biochim Biophys Acta. 1987 Nov 5;916(1):1-4. DOI:10.1016/0167-4838(87)90203-2
[2] Potempa J, et, al. Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis. J Biol Chem. 1998 Aug 21;273(34):21648-57. DOI:10.1074/jbc.273.34.21648 |
| | H-Gly-Arg-pNA Preparation Products And Raw materials |
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