- Piperonylic acid
-
- $0.00 / 25Kg/Drum
-
2026-02-17
- CAS:94-53-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 200mt/year
- Piperonylic acid
-
- $0.00 / 1g
-
2026-02-02
- CAS:94-53-1
- Min. Order: 10mg
- Purity: 99%HPLC
- Supply Ability: 2000tons
- Piperonylic acid
-
- $10.00 / 1KG
-
2026-01-30
- CAS:94-53-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100 mt
|
| | Piperonylic acid Basic information |
| Product Name: | Piperonylic acid | | Synonyms: | 1,3-BENZODIOXOLE-5-CARBOXYLIC ACID;3,4-METHYLENDIOXYBENZOIC ACID;3,4-(METHYLENEDIOXY)BENZOIC ACID;RARECHEM AL BO 0210;3,4-(methylenedioxy)benzoic acid, piperonylic acid;Piperonylic acid, 98+%;PIPEROYLICACID;3,4-Methylendioxybenzoic acid 98% | | CAS: | 94-53-1 | | MF: | C8H6O4 | | MW: | 166.13 | | EINECS: | 202-342-8 | | Product Categories: | Building Blocks;C8;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Benzodiozoles, Benzodioxines & Benzodioxepines;Carboxylic Acids;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzodiozoles, Benzodioxines & Benzodioxepines;Carboxylic Acids;Quinoxalines ,Quinazolines ,Quinaldines | | Mol File: | 94-53-1.mol |  |
| | Piperonylic acid Chemical Properties |
| Melting point | 229-231 °C (lit.) | | Boiling point | 254.32°C (rough estimate) | | density | 1.3579 (rough estimate) | | refractive index | 1.5090 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 4.35±0.20(Predicted) | | form | Powder | | color | Off-white to beige | | Water Solubility | slightly soluble | | Merck | 14,7477 | | BRN | 150206 | | Cosmetics Ingredients Functions | SKIN PROTECTING
SKIN CONDITIONING | | InChI | 1S/C8H6O4/c9-8(10)5-1-2-6-7(3-5)12-4-11-6/h1-3H,4H2,(H,9,10) | | InChIKey | VDVJGIYXDVPQLP-UHFFFAOYSA-N | | SMILES | OC(=O)c1ccc2OCOc2c1 | | LogP | 0.810 (est) | | CAS DataBase Reference | 94-53-1(CAS DataBase Reference) | | NIST Chemistry Reference | 1,3-Benzodioxole-5-carboxylic acid(94-53-1) | | EPA Substance Registry System | 1,3-Benzodioxole-5-carboxylic acid (94-53-1) |
| | Piperonylic acid Usage And Synthesis |
| Chemical Properties | It is a white to light yellow crystalline powder, slightly soluble in water, chloroform, cold ethanol, and ether. | | Uses | Piperonylic Acid is a compound closely mimicking the structure of transcinnamic acid involved in the phenylpropanoid pathway in plant physiology. | | Definition | ChEBI: Piperonylic acid is a member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a carboxy group at position 5. It is a natural product isolated from several plant species. It is a selective mechanism-based inactivator of the trans-cinnamate 4-hydroxylase enzyme and exhibits antifungal and skin wound healing properties. It has a role as a plant metabolite, an EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor, a vulnerary and an antifungal agent. It is a member of benzodioxoles, a monocarboxylic acid and an aromatic carboxylic acid. It is a conjugate acid of a piperonylate. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 40, p. 3803, 1975 DOI: 10.1021/jo00913a051 | | Purification Methods | Crystallise the acid from EtOH or water. [Beilstein 19/7 V 300.] | | References | [1] OTTO RICHARD GOTTLIEB MAURO T M. Isolation of Piperonylic Acid from Ocotea pretiosa[J]. Nature, 1958, 182 4637: 742-743. DOI:10.1038/182742b0.
[2] SEUNG HYUN HAN. Piperonylic Acid Promotes Hair Growth by Activation of EGFR and Wnt/β-Catenin Pathway.[J]. International Journal of Molecular Sciences, 2024, 25 19. DOI:10.3390/ijms251910774.
[3] SCHALK. Piperonylic acid, a selective, mechanism-based inactivator of the trans-cinnamate 4-hydroxylase: A new tool to control the flux of metabolites in the phenylpropanoid pathway[J]. Plant Physiology, 1998, 118 1: 209-218. DOI:10.1104/pp.118.1.209. |
| | Piperonylic acid Preparation Products And Raw materials |
|