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STAT3-IN-39

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Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 021-13816613772 13816613772
Email: huahero21@sina.com
Products Intro: Product Name:STAT3-IN-39
CAS:3037596-35-0
Purity:98% Package:1g
STAT3-IN-39 Basic information
Product Name:STAT3-IN-39
Synonyms:STAT3-IN-39
CAS:3037596-35-0
MF:
MW:0
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STAT3-IN-39 Structure
STAT3-IN-39 Chemical Properties
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STAT3-IN-39 Usage And Synthesis
UsesSTAT3-IN-39 (compound 10K) is an orally active STAT3 inhibitor that exhibits excellent inhibitory activity against STAT3 phosphorylation, with an IC50 of 0.47 μM in NIH-3T3 cells. STAT3-IN-39 inhibits the TGF-β1-induced fibrotic response and blocks the epithelial-mesenchymal transition in A549. STAT3-IN-39 can be utilized in research related to idiopathic pulmonary fibrosis[1].
IC 50STAT3
References[1] Wang Y, et al. Discovery of the novel Benzo[b]thiophene 1,1-dioxide derivatives as a potent STAT3 inhibitor against idiopathic pulmonary fibrosis. Eur J Med Chem. 2023 Jan 15;246:114953. DOI:10.1016/j.ejmech.2022.114953
STAT3-IN-39 Preparation Products And Raw materials
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