- 2,2-Dimethylbutanoyl chloride
-
- $8.00 / 1KG
-
2025-09-25
- CAS:5856-77-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
|
| | 2,2-Dimethylbutyryl chloride Basic information |
| Product Name: | 2,2-Dimethylbutyryl chloride | | Synonyms: | 2,2-Dimethylbutyricacidchloride;2,2-dimethylbutanoyl chloride;2,2-DIMETHYLBUTYRYL CHLORIDE;Dimethylbutyrylchloride;2,2-dimethylbutyl chloride;2,2 DiMethylbutiryl chloride;2,2-dimethylbutyryl chloride / simvastatin intermediate;2,2-DimethylbutyrylChloride> | | CAS: | 5856-77-9 | | MF: | C6H11ClO | | MW: | 134.6 | | EINECS: | 227-478-5 | | Product Categories: | intermediate | | Mol File: | 5856-77-9.mol |  |
| | 2,2-Dimethylbutyryl chloride Chemical Properties |
| Melting point | -20 °C | | Boiling point | 133°C | | density | 0,98 g/cm3 | | refractive index | 1.4240 | | Fp | 29°C | | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | | solubility | Chloroform, Ethyl Acetate | | form | Oil | | color | Clear Colorless | | Water Solubility | Reacts with water. Soluble in chloroform and ethyl acetate. | | Sensitive | Moisture Sensitive | | BRN | 1743935 | | InChI | InChI=1S/C6H11ClO/c1-4-6(2,3)5(7)8/h4H2,1-3H3 | | InChIKey | LDJUYMIFFNTKOI-UHFFFAOYSA-N | | SMILES | C(Cl)(=O)C(C)(C)CC | | CAS DataBase Reference | 5856-77-9(CAS DataBase Reference) |
| Hazard Codes | C | | Risk Statements | 10-34-43 | | Safety Statements | 26-36/37/39-45-36/37-20 | | RIDADR | 2924 | | WGK Germany | WGK 3 | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29159000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Dam. 1
Skin Sens. 1 |
| | 2,2-Dimethylbutyryl chloride Usage And Synthesis |
| Chemical Properties | Colorless liquid | | Uses | ,2-Dimethylbutanoyl chloride is a reagent that is used in the synthesis of 4α,5-Dihydro Simvastatin, the drug, is sold under the trade name Zocor. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. | | Synthesis | Under stirring, 25.6g of 2,2-dimethylbutyric acid and 35.8g of sulfoxide chloride were added to a three-necked flask, heated to reflux, and the hydrogen chloride and sulfur dioxide gases were absorbed with alkali. After no gas was produced, the excess sulfoxide was evaporated, and then 2,2-dimethylbutyryl chloride was obtained by distillation under reduced pressure as 26.9g, with 90% yield. |
| | 2,2-Dimethylbutyryl chloride Preparation Products And Raw materials |
|