Histone H3.3G34W Rabbit Monoclonal Antibody - Biotinylated (Clone RM263)

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Histone H3.3G34W Rabbit Monoclonal Antibody - Biotinylated (Clone RM263) Basic information
Product Name:Histone H3.3G34W Rabbit Monoclonal Antibody - Biotinylated (Clone RM263)
Synonyms:Histone H3.3G34W Rabbit Monoclonal Antibody - Biotinylated (Clone RM263)
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Histone H3.3G34W Rabbit Monoclonal Antibody - Biotinylated (Clone RM263) Structure
Histone H3.3G34W Rabbit Monoclonal Antibody - Biotinylated (Clone RM263) Chemical Properties
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Histone H3.3G34W Rabbit Monoclonal Antibody - Biotinylated (Clone RM263) Usage And Synthesis
DescriptionHistone H3 is a nuclear protein and component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei.1 It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications (PTMs). Metazoans have three histone variants: canonical histone H3.1, DNA replication-independent histone H3.3, and the centromeric variant CENP-A.2 Histone H3.3 is incorporated into chromatin in a DNA replication-independent manner at sites of active transcription.2,3,4 Histone H3.3G34W is a point mutation expressed in giant cell tumors of bone (GCTBs) and is associated with tumor recurrence and metastasis.5 Cayman's Histone H3.3G34W Rabbit Monoclonal Antibody (Clone RM263) - Biotinylated can be used for chromatin immunoprecipitation (ChIP), ELISA, immunohistochemistry (IHC), and Western blot (WB) applications.WARNING This product is not for human or veterinary use.
Histone H3.3G34W Rabbit Monoclonal Antibody - Biotinylated (Clone RM263) Preparation Products And Raw materials
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