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| | 10,11-DIHYDROCARBAMAZEPINE Basic information |
| Product Name: | 10,11-DIHYDROCARBAMAZEPINE | | Synonyms: | f)azepine-5-carboxamide,10,11-dihydro-5h-dibenz(;10,11-DIHYDRO-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE;10,11-DIHYDROCARBAMAZEPINE;10,11-Dihydro-5H-dibenzo[b,f]azepine-5-carboxamide;10,11-Dihydro5H-dibenzo[b,f]azepine-5-carboxamide;10,11-Dihydrocarbamazepine,99%;5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide;10,11-Dihydrocarbamazepine,10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide | | CAS: | 3564-73-6 | | MF: | C15H14N2O | | MW: | 238.28 | | EINECS: | 222-649-0 | | Product Categories: | Amines, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Amines;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 3564-73-6.mol |  |
| | 10,11-DIHYDROCARBAMAZEPINE Chemical Properties |
| Melting point | 205-210 °C(lit.) | | Boiling point | 394.5±52.0 °C(Predicted) | | density | 1.232±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | dichloromethane: soluble2.5%, clear, colorless | | pka | 14.07±0.20(Predicted) | | form | Solid | | color | White to Off-White | | Water Solubility | Soluble in dichloromethane. Insoluble in water. | | BRN | 196969 | | Major Application | forensics and toxicology
pharmaceutical (small molecule) | | InChI | 1S/C15H14N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-8H,9-10H2,(H2,16,18) | | InChIKey | PHNLCHMJDSSPDQ-UHFFFAOYSA-N | | SMILES | NC(=O)N1c2ccccc2CCc3ccccc13 |
| Hazard Codes | Xn | | Risk Statements | 22-42/43 | | Safety Statements | 22-24/25-45-36/37 | | WGK Germany | 3 | | RTECS | HN8300000 | | HS Code | 29339900 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 4 Oral
Repr. 1A
Skin Sens. 1A
STOT SE 3 |
| | 10,11-DIHYDROCARBAMAZEPINE Usage And Synthesis |
| Chemical Properties | white crystals or needles | | Uses | A dihydro impurity of Carbamazepine (C175840) | | Uses | 10,11-Dihydrocarbamazepine is used as internal standard during simultaneous determination of carbamazepine and its active metabolite in plasma by liquid chromatography. It can be used in chemiluminescence method for determination of carbamazepine. | | General Description | 10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug used in the treatment of epilepsy. Single-crystal structure of new dimer-based polymorph of 10,11-dihydrocarbamazepine has been investigated. |
| | 10,11-DIHYDROCARBAMAZEPINE Preparation Products And Raw materials |
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