3-[5-({3-[2-(4-fluoroanilino)-2-oxoethyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene}methyl)-2-furyl]-2-methylbenzoic acid manufacturers
- ZINC17167211
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- $2500.00
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2026-08-04
- CAS:592539-21-4
- Purity:
- Supply Ability: 10g
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| | 3-[5-({3-[2-(4-fluoroanilino)-2-oxoethyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene}methyl)-2-furyl]-2-methylbenzoic acid Basic information |
| | 3-[5-({3-[2-(4-fluoroanilino)-2-oxoethyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene}methyl)-2-furyl]-2-methylbenzoic acid Chemical Properties |
| density | 1.503±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 3.783±0.10(predicted) |
| | 3-[5-({3-[2-(4-fluoroanilino)-2-oxoethyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene}methyl)-2-furyl]-2-methylbenzoic acid Usage And Synthesis |
| Description | ZINC17167211 is a selective agonist of peroxisome proliferator activated receptors-α (PPAR-α). | | Uses | ZINC17167211 is a potent PPAR-α agonist (EC50=0.16 nM) that can be used in the study of diabetes, hyperlipidemia, and inflammatory diseases[1]. | | IC 50 | PPAR-α: 0.16 nM (EC50) | | References | [1] Gangwal, et al. "Biological evaluation and structural insights for design of subtype-selective peroxisome proliferator activated receptor-α (PPAR-α) agonists." Bioorganic & Medicinal Chemistry Letters 25.2 (2015): 270-275. DOI:10.1016/j.bmcl.2014.11.052 |
| | 3-[5-({3-[2-(4-fluoroanilino)-2-oxoethyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene}methyl)-2-furyl]-2-methylbenzoic acid Preparation Products And Raw materials |
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