- EDTA-4NA
-
-
2026-06-12
- CAS:13235-36-4
- Min. Order: 1KG
- Purity: 99.0%min
- Supply Ability: 20 tons
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| Product Name: | Ethylenediaminetetraacetic acid tetrasodium salt | | Synonyms: | ETHYLENEDIAMINETETRAACETIC ACID TETRASODIUM SALT TETRAHYDRATE;[ETHYLENEDINITRILO]TETRAACETIC ACID TETRASODIUM SALT TETRAHYDRATE;EDTA, TETRA SODIUM SALT, TETRAHYDRATE;EDTA-4NA TETRAHYDRATE;TETRASODIUM SALT OF EDTA TETRA HYDRATE;ETHYLENEDIAMINETETRAACETIC ACID TETRASODIUM SALT HYDRATE PRACTICAL GRADE;ETHYLENEDIAMINETETRAACETIC ACID TETRASODIUM SALT HYDRATE PURUM;Trilon B(EDTA-4Na) | | CAS: | 13235-36-4 | | MF: | C10H19N2NaO9 | | MW: | 334.26 | | EINECS: | 603-569-9 | | Product Categories: | | | Mol File: | 13235-36-4.mol |  |
| | Ethylenediaminetetraacetic acid tetrasodium salt Chemical Properties |
| storage temp. | Inert atmosphere,Room Temperature | | solubility | H2O: 0.1 M at 20 °C, clear, colorless | | form | Solid | | color | White crystalline | | Odor | Odorless | | Water Solubility | almost transparency | | InChI | InChI=1S/C10H16N2O8.Na.H2O.H/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;1H2; | | InChIKey | LHCZUGDUAQREMU-UHFFFAOYSA-N | | SMILES | N(CC(=O)O)(CC(=O)O)CCN(CC(=O)O)CC(=O)O.[NaH].O | | CAS DataBase Reference | 13235-36-4(CAS DataBase Reference) | | EPA Substance Registry System | Tetrasodium ethylenediaminetetraacetate tetrahydrate (13235-36-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | HS Code | 2922.49.8000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | Ethylenediaminetetraacetic acid tetrasodium salt Usage And Synthesis |
| Description | Ethylenediaminetetraacetic acid tetrasodium salt (also named as sodium edetate) can be formed by reacting a basic solution of ethylenediamine with formaldehyde and sodium or hydrogen cyanide, followed by hydrolysis to form the salt. It can also be produced by using excess sodium hydroxide in the reaction.1 In medicine, sodium edetate is used a s chelating agent to remove heavy metal, such as lead or mercury, from the blood. It is used to lower blood levels of calcium, to control heart rhythm disturbances cased by a heart medication.2 In food industry, it is used as an additive in flume water for washing fruits and vegetables. In industry, it is used in the formulations of anti-adhesive agents, corrosion inhibitors, anti-scaling agents, lubricant additives, surface active agents, etc.3,4 It is also used in photo-chemicals, textile treatment products and dyes, biocides (e.g. disinfectants, pest control products) and polishes and waxes.5
| | References | - https://pubchem.ncbi.nlm.nih.gov/compound/16211056#section=Top
- https://www.drugs.com/mtm/edetate-disodium-edta.html
- http://www.efsa.europa.eu
- http://www.speiko.de
https://echa.europa.eu/substance-information/-/substanceinfo/100.000.522
[1] Jae Hyeon Jo. (2019). New Insight into Ethylenediaminetetraacetic Acid Tetrasodium Salt as a Sacrificing Sodium Ion Source for Sodium-Deficient Cathode Materials for Full Cells. ACS Applied Materials & Interfaces, 11 6, 5957–5965. https://doi.org/10.1021/acsami.8b1848
[2] Kate McKey. (2025). Piloting 4% Tetrasodium Ethylenediaminetetraacetic Acid (T-EDTA) Catheter Lock Solution in Renal Hemodialysis: A Quality Improvement Evaluation. Journal of Infusion Nursing, 48 6, 412–421. https://doi.org/10.1097/NAN.0000000000000620
[3] Jocelyn Hill, Rachel G. (2021). Efficacy of 4% tetrasodium ethylenediaminetetraacetic acid (T-EDTA) catheter lock solution in home parenteral nutrition patients: A quality improvement evaluation. Journal of Vascular Access, 22 4, 533–539. https://doi.org/10.1177/1129729820946916
| | Uses | Ethylenediaminetetraacetic Acid Tetrasodium Salt is a chelator used to eliminate inhibition of enzyme catalyzed reactions. It can be used as reactant/reagent for green preparation of O-allylhydroxylamines via organocatalytic oxidation of tertiary allylic amines followed by a [2,3]-Meisenheimer rearrangement. | | Application | Ethylenediaminetetraacetic acid tetrasodium salt (T-EDTA) can be used as a catheter locking solution for patients undergoing renal haemodialysis and those receiving home parenteral nutrition. A 4% T-EDTA catheter locking solution significantly reduces the risk of complications associated with central venous access devices, such as occlusion and catheter-related infections[2-3]. | | Biological Activity | Primary Target
H+-ATPase | | Materials Uses | Ethylenediaminetetraacetic acid tetrasodium salt (EDTA-4Na) can serve as an additional source of Na⁺ ions, helping to increase the charge capacity[1]. | | Properties and Applications |
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INDEX/GRADE
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SPECIFICATION
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Appearance
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White crystal powder
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Purity
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99% min
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Chloride (Cl
-
)
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0.01% max
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Sulfate(SO4
2-
)
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0.05% max
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|
Pb
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0.001% max
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Fe
|
0.001% max
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Chelation value
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220mg CaCO3/g min
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pH value
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10.5-11.5
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NTA
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1% max
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| | Ethylenediaminetetraacetic acid tetrasodium salt Preparation Products And Raw materials |
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