| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Email: |
eric_feng1954@126.com |
| Products Intro: |
Product Name:T-Type Ca2+ channel inhibitor CAS:1072018-68-8 Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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| Company Name: |
Aikon International Limited
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| Tel: |
025-58859352 13913916777 |
| Email: |
dt3@aikonchem.com |
| Products Intro: |
Product Name:(S)-3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide CAS:1072018-68-8 Purity:95% HPLC or GC Package:10G,5G;1G
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3,5-Dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide manufacturers
- TTA-P2
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- $4910.00
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2026-05-25
- CAS:1072018-68-8
- Purity:
- Supply Ability: 10g
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| | 3,5-Dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide Basic information |
| Product Name: | 3,5-Dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide | | Synonyms: | T-Type Ca2+ channel inhibitor;(S)-3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)meth;(S)-3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide;(S)-3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)m;3,5-Dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide;BenzaMide, 3,5-dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-diMethyl-2H-pyran-4-yl]Methyl]-4-piperidinyl]Methyl]-;3,5-DICHLORO-N-[1-(2,2-DIMETHYL-TETRAHYDRO-PYRAN-4-YLMETHYL)-4-FLUORO-PIPERIDIN-4-YLMETHYL]-BENZAMIDE;T-Type calcium channel inhibitor(TTA-P2) | | CAS: | 1072018-68-8 | | MF: | C21H29Cl2FN2O2 | | MW: | 431.37 | | EINECS: | | | Product Categories: | | | Mol File: | 1072018-68-8.mol | ![3,5-Dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide Structure](CAS/GIF/1072018-68-8.gif) |
| | 3,5-Dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide Chemical Properties |
| Boiling point | 510.1±50.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | pka | 13.65±0.46(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | 3,5-Dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide Usage And Synthesis |
| Uses | TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease[1]. | | References | [1] Chemin J, et al. De novo mutation screening in childhood-onset cerebellar atrophy identifies gain-of-function mutations in the CACNA1G calcium channel gene. Brain. 2018;141(7):1998-2013. DOI:10.1093/brain/awy145 |
| | 3,5-Dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide Preparation Products And Raw materials |
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