Abacavir 5’-Phosphate

Request For Quotation
Abacavir 5’-Phosphate Suppliers list
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:Abacavir 5'-Phosphate
CAS:136470-77-4
Purity:> 95% Remarks:Please reach out to us for more information about custom solutions.
Company Name: NewCan Biotech Limited
Tel: +86-571-86912261 19975279805
Email: sales@newcanbio.com
Products Intro: Product Name:Abacavir5'-Phosphate
CAS:136470-77-4
Purity:97% Package:mgs,gs,kgs
Company Name: J & K SCIENTIFIC LTD.  
Tel: 18210857532; 18210857532
Email: jkinfo@jkchemical.com
Products Intro: Product Name:Abacavir 5'-Phosphate
CAS:136470-77-4
Package:2.5Mg,25Mg
Company Name: Chemsky（shanghai）International Co.,Ltd.  
Tel: 021-50135380
Email: shchemsky@sina.com
Products Intro: Product Name:Abacavir 5'-Phosphate
CAS:136470-77-4
Purity:98%
Company Name: Clearsynth Labs Limited  
Tel: +91-22-26355700
Email: info@clearsynth.com
Products Intro: Product Name:Abacavir 5'-Phosphate
CAS:136470-77-4
Remarks:CS-T-00007
Abacavir 5’-Phosphate Basic information
Product Name:Abacavir 5’-Phosphate
Synonyms:[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate;Abacavir 5’-Phosphate;(1S,4R)- 4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-Methanol Dihydrogen Phosphate (Ester);(1S-cis)-Abacavir Monophosphate;((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl dihydrogen phosphate;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, 1-(dihydrogen phosphate), (1S,4R)-;Abacavir Impurity 13;Abacavir 5'-Phosphate
CAS:136470-77-4
MF:C14H19N6O4P
MW:366.31
EINECS:
Product Categories:Bases & Related Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Nucleotides;Pharmaceuticals;Phosphorylating and Phosphitylating Agents
Mol File:136470-77-4.mol
Abacavir 5’-Phosphate Structure
Abacavir 5’-Phosphate Chemical Properties
Melting point 189-194°C (dec.)
Boiling point 749.3±70.0 °C(Predicted)
density 1.93±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Methanol, Water
pka1.91±0.10(Predicted)
form Solid
color White
Safety Information
MSDS Information
Abacavir 5’-Phosphate Usage And Synthesis
Chemical PropertiesWhite Solid
UsesAbacavir 5’-Phosphate (Abacavir - In House Impurity) is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
DefinitionChEBI: Abacavir monophosphate is the organic phosphate that is the 5'-monophosphate of abacavir. It has a role as a metabolite. It is a member of 2,6-diaminopurines and an organic phosphate. It is functionally related to an abacavir.
Abacavir 5’-Phosphate Preparation Products And Raw materials
Tag:Abacavir 5’-Phosphate(136470-77-4) Related Product Information
Abacavir 2,6-Diaminopurine (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol Abacavir 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)- trans-Abacavir Hydrochloride 2-Amino-6-cyclopropylamino-9H-purine (1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride Abacavir Abacavir 5'-Glucuronide Abacavir Abacavir-d4 Abacavir Related CoMpound D Abacavir Carboxylate (1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride Abacavir sulfate 6-aminocarbovir Abacavir Impurity 1