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Product Name:KH 7;(±)-2-(1H-benziMidazol-2-ylthio)propanoicacid2-[(5-broMo-2-hydroxyphenyl)Methylene]hydrazide
CAS:330676-02-3
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide manufacturers
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| | (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Basic information |
| Product Name: | (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide | | Synonyms: | (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide;KH 7;(E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N′-(5-bromo-2-hydroxybenzylidene)propanehydrazide;sAC inhibitor KH7;Propanoic acid, 2-(1H-benzimidazol-2-ylthio)-, 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide;inhibit,KH 7,Adenylate Cyclase,Adenylyl cyclase,KH7,Inhibitor,KH-7;2-((1H-Benzo[d]imidazol-2-yl)thio)-N'-(5-bromo-2-hydroxybenzylidene)propanehydrazide;KH7, 10 mM in DMSO | | CAS: | 330676-02-3 | | MF: | C17H15BrN4O2S | | MW: | 419.3 | | EINECS: | | | Product Categories: | | | Mol File: | 330676-02-3.mol | ![(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Structure](CAS/20181012/GIF/330676-02-3.gif) |
| | (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Chemical Properties |
| density | 1.61±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: >20mg/mL | | form | powder | | pka | 7.90±0.48(Predicted) | | color | White to light yellow |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45 | | RIDADR | UN 2811 6.1 / PGIII |
| | (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Usage And Synthesis |
| Uses | KH7 has been used:
- as a soluble adenyl?cyclase?(sAC) antagonist to study its effect on the signaling pathway mediated by the action of transient? receptor type 1 (TRPV1) in sperm cells.
- as a selective sAC antagonist to study its effect on the signaling pathway of proton gated channels (HV1) induced action in sperm cells.
- as a sAC inhibitor to study its effects on cAMP increase in monophosphorylated myosin light chain (pMLC).
| | Biochem/physiol Actions | KH7 is a selective inhibitor of soluble adenylyl cyclase. Soluble adenylyl cyclase (sAC) is an ubiquitously expressed, essential component of cAMP-signaling. | | storage | Store at +4°C |
| | (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Preparation Products And Raw materials |
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