N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide

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Products Intro: Product Name:Procaspase-3 activator 1541
CAS:1100353-03-4
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
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Products Intro: Product Name:CASP3 Activator 1541
CAS:1100353-03-4
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Products Intro: Product Name:Procaspase-3 activator 1541
CAS:1100353-03-4
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Products Intro: Product Name:CASP3 Activator 1541
CAS:1100353-03-4
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CAS:1100353-03-4
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N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide manufacturers

  • CASP3 Activator 1541
  • CASP3 Activator 1541 pictures
  • $30.00 / 1mg
  • 2026-05-11
  • CAS:1100353-03-4
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  • Purity: 99.98%
  • Supply Ability: 10g
N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide Basic information
Product Name:N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide
Synonyms:N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide;N-(3-imidazo[1,2-a]pyridin-2-ylphenyl)-8-methoxy-2-oxochromene-3-carboxamide;Procaspase-3 activator 1541;CASP3 Activator 1541;CASP-3 Activator 1541,CASP3 Activator 1541;2H-1-Benzopyran-3-carboxamide, N-(3-imidazo[1,2-a]pyridin-2-ylphenyl)-8-methoxy-2-oxo-;CASP3 Activator 1541, 10 mM in DMSO
CAS:1100353-03-4
MF:C24H17N3O4
MW:411.41
EINECS:
Product Categories:
Mol File:1100353-03-4.mol
N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide Structure
N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide Chemical Properties
density 1.35±0.1 g/cm3(Predicted)
storage temp. 2-8°C
form Solid
pka11.58±0.70(Predicted)
color Light yellow to yellow
Safety Information
MSDS Information
N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide Usage And Synthesis
UsesProcaspase-3/6 activator 1 (compound 1541) is a highly specific and robust activator of executioner procaspases-3 and -6, with EC50 values of 2.4 ± 0.2 and 2.8 ± 0.3 μM, respectively. Procaspase-3/6 activator 1 does not activate procaspases-1 or -7[1].
IC 50Procaspase-3: 2.4 ± 0.2 μM (EC50); Procaspase-6: 2.8 ± 0.3 μM (EC50)
References[1] Wolan DW, et al. Small-molecule activators of a proenzyme. Science. 2009 Nov 6;326(5954):853-8. DOI:10.1126/science.1177585
N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide Preparation Products And Raw materials
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