1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- manufacturers
- Biotin alkyne
-
- $0.00 / 250mg
-
2025-06-07
- CAS:773888-45-2
- Min. Order: 250mg
- Purity: >95.00%
- Supply Ability: 250mg
|
| | 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- Basic information |
| Product Name: | 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- | | Synonyms: | 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)-;N-(Prop-2-ynyl)biotinamide;N-Propargylbiotinamide;1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-2-oxo-N-2-propyn-1-yl-, (3aS,4S,6aR)-;N-Propargylbiotinamide/1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-2-oxo-N-2-propyn-1-yl-, (3aS,4S,6aR);5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(2-propyn-1-yl)pentanamide;Biotin alkyne - [B6020] | | CAS: | 773888-45-2 | | MF: | C13H19N3O2S | | MW: | 281.37 | | EINECS: | | | Product Categories: | | | Mol File: | 773888-45-2.mol | ![1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- Structure](CAS/GIF/773888-45-2.gif) |
| | 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- Chemical Properties |
| Melting point | 169-170 °C | | Boiling point | 614.8±50.0 °C(Predicted) | | density | 1.185±0.06 g/cm3(Predicted) | | storage temp. | -20°C, sealed storage, away from moisture | | solubility | good in DMSO and DMF, | | form | Solid | | pka | 13.90±0.40(Predicted) | | color | White to off-white | | Appearance | colorless solid | | Water Solubility | low in water |
| | 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- Usage And Synthesis |
| Description | Biotin alkyne is a biotinylated compound that enables simple biotinylation of antibodies, proteins and any other azide-containing biomolecules. The alkyne group of this reagent can react with azide moiety in Cu(I)-catalyzed Click Chemistry reaction to form a stable triazole linkage. | | Uses | Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs | | References | [1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014. DOI:10.1016/j.chembiol.2020.07.020 |
| | 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- Preparation Products And Raw materials |
|