2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]-

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2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- manufacturers

2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- Basic information

Product Name:	2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]-
Synonyms:	2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]-;Decarbonyl Rivaroxaban;Imp. G:5-chloro-N-((2R)-2-hydroxy-3-{[4-(3-oxo-4-morpholinyl)-phenyl]amino}propyl)-2-thiophenecarboxamide;Rivaroxaban impurity P4D-P;Rivaroxaban Descarbonyl Impurity;Rivaroxaban L;5-chloro-N-((2R)-2-hydroxy-3-{[4-(3-oxo-4-morpholinyl)-phenyl]amino}propyl)-2-thiophenecarboxamide;Rivaroxaban Impurity 12/Decarbonyl Rivaroxaban/Rivaroxaban Impurity G
CAS:	721401-53-2
MF:	C18H20ClN3O4S
MW:	409.89
EINECS:
Product Categories:
Mol File:	721401-53-2.mol

2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- Chemical Properties

Melting point	>188°C (dec.)
Boiling point	772.6±60.0 °C(Predicted)
density	1.434±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	13.65±0.46(Predicted)
form	Solid
color	White to Off-White
Stability:	Hygroscopic
Major Application	pharmaceutical small molecule
InChI	1S/C18H20ClN3O4S/c19-16-6-5-15(27-16)18(25)21-10-14(23)9-20-12-1-3-13(4-2-12)22-7-8-26-11-17(22)24/h1-6,14,20,23H,7-11H2,(H,21,25)/t14-/m1/s1
InChIKey	OKMRQXXUAFSBCM-CQSZACIVSA-N
SMILES	[s]1c(ccc1C(=O)NC[C@H](O)CNc2ccc(cc2)N3CCOCC3=O)Cl

Safety Information

WGK Germany	WGK 3
Storage Class	11 - Combustible Solids

MSDS Information

2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- Usage And Synthesis

Uses	Decarbonyl Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.

2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- Preparation Products And Raw materials

Preparation Products

Tag:2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]-(721401-53-2) Related Product Information

1,2-BenzenedicarboxaMide, N1,N2-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- Rivaroxaban-d4 5-R-Rivaroxaban Rivaroxaban 3-Chlorothiophene-2-carboxylic acid Benzoic acid, 2-[[[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]aMino]carbonyl]- Rivaroxaban Diol (Mixture of Diastereomers) (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl 3-Morpholinone, 4-(2,4-diaMinophenyl)- (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide Rivaroxaban Impurity 27 Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- 2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl- 5-Methyl-2-thiophenecarboxylic acid (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione 2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione 4-Chlorothiophene-2-carboxylic acid 2,5-Dichlorothiophene-3-carboxylic acid