| Company Name: |
TCI Europe |
| Tel: |
320-37350700 |
| Email: |
sales@tcieurope.eu |
| Company Name: |
TCI AMERICA |
| Tel: |
800-4238616 |
| Email: |
sales@tciamerica.com |
|
| | DHR 6G [DihydrorhodaMine 6G] Basic information |
| Product Name: | DHR 6G [DihydrorhodaMine 6G] | | Synonyms: | DHR 6G [DihydrorhodaMine 6G];D 633;D-r 6g;Benzoic acid, 2-[3,6-bis(ethylamino)-2,7-dimethyl-9H-xanthen-9-yl]-, ethyl ester;DHR 6G;ethyl 2-(3,6-bis(ethylamino)-2,7-dimethyl-9H-xanthen-9-yl)benzoate;2-[3,6-Bis(ethylamino)-2,7-dimethyl-9H-xanthen-9-yl]benzoic Acid Ethyl Ester | | CAS: | 217176-83-5 | | MF: | C28H32N2O3 | | MW: | 444.57 | | EINECS: | | | Product Categories: | Xanthene | | Mol File: | 217176-83-5.mol | ![DHR 6G [DihydrorhodaMine 6G] Structure](CAS/20180808/GIF/217176-83-5.gif) |
| | DHR 6G [DihydrorhodaMine 6G] Chemical Properties |
| solubility | Soluble in N,N-dimethylformamide, dimethyl
sulfoxide, methanol | | form | Solid | | pka | 4.97 ± 0.40, most basic, temperature:
25 °C | | color | Light pink solid | | λmax | 296 nm | | Biological Applications | Detecting genetic anomalies,methylation in DNA,intracellular hydrogen peroxide in tumor cells,intracellular active oxygen and reduced glutathione,gene expression,7reactive oxygen species (ROS),small RNAs; nucleic acid ligation assays | | Major Application | Light-transmitting
materials/construction boards |
| | DHR 6G [DihydrorhodaMine 6G] Usage And Synthesis |
| Uses | Dihydrorhodamine 6G (DHR 6G) is the reduced form of Rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide[1]. | | References | [1] Yong Qin, et al. Dihydrorhodamine 123 is superior to 2,7-dichlorodihydrofluorescein diacetate and dihydrorhodamine 6G in detecting intracellular hydrogen peroxide in tumor cells. Cell Biol Int. 2008 Feb;32(2):224-8. DOI:10.1016/j.cellbi.2007.08.028 |
| | DHR 6G [DihydrorhodaMine 6G] Preparation Products And Raw materials |
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