2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid

2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid Suppliers list

Company Name:	Jiangsu Yutian pharmaceutical Co.,Ltd.
Tel:	+undefined-0518-86098006 +undefined19851887368
Email:	lvan.hui@jsytsw.com
Products Intro:	Product Name:2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid CAS:1211443-58-1 Purity:99% Package:25kg

Company Name:	ANHUI CHICO CHEMICAL CO., LTD.
Tel:	+8613057662806
Email:	kirsten@chicopharm.com
Products Intro:	Product Name:2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid CAS:1211443-58-1 Purity:99.0% Package:100KG;25KG;1KG;

Company Name:	Capot Chemical Co.,Ltd.
Tel:	+86-（0）57185586718; +8613336195806
Email:	sales@capot.com
Products Intro:	Product Name:2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid CAS:1211443-58-1 Purity:NLT 98% Package:1G;1KG;100KG

Company Name:	Beijing Cooperate Pharmaceutical Co.,Ltd
Tel:	010-60279497
Email:	sales01@cooperate-pharm.com
Products Intro:	Product Name:2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid CAS:1211443-58-1 Purity:98% Package:100G;1KG;5KG;10KG;25KG;50KG;100KG

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	+undefined-21-51877795
Email:	ivan@atkchemical.com
Products Intro:	Product Name:2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid CAS:1211443-58-1 Purity:98% Package:500MG;1G;5G;10G;50G;100G

2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid manufacturers

2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid Basic information

Product Name:	2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid
Synonyms:	2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid;Ribociclib Intermediate 1;7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 2-chloro-7-cyclopentyl-;2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxy...;2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d];Ribociclib Impurity 53
CAS:	1211443-58-1
MF:	C12H12ClN3O2
MW:	265.7
EINECS:	1592732-453-0
Product Categories:
Mol File:	1211443-58-1.mol

2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid Chemical Properties

density	1.61±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	3.63±0.30(Predicted)
Appearance	White to light yellow Solid
InChI	InChI=1S/C12H12ClN3O2/c13-12-14-6-7-5-9(11(17)18)16(10(7)15-12)8-3-1-2-4-8/h5-6,8H,1-4H2,(H,17,18)
InChIKey	LXCZVGKSFJMLRO-UHFFFAOYSA-N
SMILES	C1(Cl)=NC=C2C=C(C(O)=O)N(C3CCCC3)C2=N1

Safety Information

MSDS Information

2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid Usage And Synthesis

Uses	2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid can be used as an intermediate in organic and pharmaceutical synthesis.
Synthesis	1211443-55-8 1211443-58-1 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde (2.69 g, 11 mmol) was used as starting material and dissolved in DMF. Subsequently, Oxone (7.2 g, 12 mmol) was added to this solution and the reaction was stirred at room temperature for 6 hours. After completion of the reaction, water was added to the reaction mixture to precipitate the target product. The yellow solid, 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid (2.69 g, 85% yield) was collected by filtration. Mass spectrum (ESI) m/z 266 [M + H]+.
References	[1] Patent: WO2010/20675, 2010, A1. Location in patent: Page/Page column 91

2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid Preparation Products And Raw materials

Raw materials	POTASSIUM PEROXYMONOSULFATE-->Ribociclib intermediate-->N,N-Dimethylformamide
Preparation Products	2-Chloro-7-cyclopentyl-N,N-dimethyl-H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

Tag:2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid(1211443-58-1) Related Product Information

(2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyriMidin-6-yl)Methanol 2-Chloro-7-cyclopentyl-N,N-dimethyl-H-pyrrolo[2,3-d]pyrimidine-6-carboxamide