Colby trifluoromethylation reagent

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Colby trifluoromethylation reagent Basic information
Product Name:Colby trifluoromethylation reagent
Synonyms:Colby trifluoromethylation reagent;Hexafluoroacetone hydrate-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt;Hexafluoroacetone hydrate-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt AldrichCPR;1,1,1,3,3,3-Hexafluoropropane-2,2-diol-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt
CAS:1400691-55-5
MF:C12H18F6N2O2
MW:336.28
EINECS:
Product Categories:
Mol File:1400691-55-5.mol
Colby trifluoromethylation reagent Structure
Colby trifluoromethylation reagent Chemical Properties
form solid
SMILESOC([O-])(C(F)(F)F)C(F)(F)F.C1CCC2=[N+](CC1)CCCN2
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Eye Dam. 1
MSDS Information
Colby trifluoromethylation reagent Usage And Synthesis
UsesThe Colby Trifluoromethylation Reagent is an air-stable, white solid, which can be used as a source of fluoroform through the release of trifluoroacetate. This reagent can add trifluoromethyl groups in a nucleophlic fashion to carbonyls and sulfides.
General DescriptionColby trifluoromethylation reagent is an amidinate salt of hexafluoroacetone hydrate. This reagent can be prepared from the ethereal solution of hexafluoroacetone trihydrate. It undergoes various trifluoromethylation reactions with electrophiles under different reaction conditions to afford trifluoromethylated products.
Colby trifluoromethylation reagent Preparation Products And Raw materials
Preparation Products2,2,2-Trifluoro-1,1-bis(4-methoxyphenyl)ethanol-->1-(4-(diMethylaMino)phenyl)-2,2,2-trifluoroethanol
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