(T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-O3,O5]difluoroboron
概述 用途与合成方法 MSDS (T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-O3,O5]difluoroboron价格(试剂级) 上下游产品信息
| 中文名称 | (T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-O3,O5]difluoroboron |
|---|---|
| 中文同义词 | 化合物CRANAD 2;(T-4)-[(1E,6E)-1,7-双[4-(二甲基氨基)苯基]-1,6-庚二烯-3,5-DIONATO-ΚO3,ΚO5]二氟硼;CRANAD-2,近红外淀粉样Β荧光探针;CRANAD-2,NEAR-INFRARED AMYLOID-BETA FLUORESCENT PROBE;CRANAD 2[SML0842] |
| 英文名称 | (T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-O3,O5]difluoroboron |
| 英文同义词 | (T-4)-[(1E,6E)-1,7-Bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-kO3,kO5]difluoroboron;(T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-?O3,?O5]difluoroboron;CRANAD 2;4,6-bis(4-dimethylaminophenyl styryl)- 2,2-difluoro-(1,3,2) dioxaborinin-4-ene-1-ium-2-uide;Boron, [(1E,6E)-1,7-bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-κO3,κO5]difluoro-, (T-4)- (ACI);inhibit,CRANAD-2,CRANAD 2,CRANAD2,Abeta,Amyloid-β,β-amyloid peptide,Inhibitor;(T -4)-[(1E ,6E )-1,7-Bis[4-(dimethylamino) phenyl]-1,6-heptadiene-3,5-dionato-κO ,κO ] difluoroboron;CRANAD-2, Near-infrared Amyloid-beta fluorescent probe |
| CAS号 | 1193447-34-5 |
| 分子式 | C23H25BF2N2O2 |
| 分子量 | 410.2646064 |
| EINECS号 | |
| 相关类别 | 染料探针 |
| Mol文件 | 1193447-34-5.mol |
| 结构式 | ![(T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-O3,O5]difluoroboron 结构式](CAS/20180713/GIF/1193447-34-5.gif) |
(T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-O3,O5]difluoroboron 性质
| 储存条件 | 2-8°C |
|---|---|
| 溶解度 | DMSO：可溶，0.2mg/mL，澄清（加热） |
| 形态 | 粉末 |
| 颜色 | 深蓝色到黑色 |
| InChI | 1S/C23H25BF2N2O2/c1-27(2)20-11-5-18(6-12-20)9-15-22-17-23(30-24(25,26)29-22)16-10-19-7-13-21(14-8-19)28(3)4/h5-17H,1-4H3/b15-9+,16-10+ |
| InChIKey | PVXQJYXODFZTBR-KAVGSWPWSA-N |
| SMILES | [B-]1([O+]=C(C=C(O1)\C=C\c3ccc(cc3)N(C)C)\C=C\c2ccc(cc2)N(C)C)(F)F |
(T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-O3,O5]difluoroboron 用途与合成方法
CRANAD-2 是一种检测 Aβ 斑块的特异性近红外 (NIR) 荧光探针。CRANAD-2 可穿透血脑屏障，并对 Aβ 聚集体具有高度亲和力，其Kd 值为38 nM。
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-103242 | (T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-O3,O5]difluoroboron CRANAD-2 | 1193447-34-5 | 50 mg | 3913元 |
| 2025/09/19 | S3405 | (T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-O3,O5]difluoroboron CRANAD-2 | 1193447-34-5 | 25mg | 6625.71元 |