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| Product Name: | RDC1 | | Synonyms: | ANTI-CXCR7 (C-TERM) antibody produced in rabbit;ANTI-CMKOR1 (C-TERM) antibody produced in rabbit;Anti-CXCR7 (N-terminal) antibody produced in rabbit;Anti-Thrombin Receptor, N-Terminal antibody produced in rabbit;Anti-PAR1 (Cleaved-Ser42), N-Terminal antibody produced in rabbit;Anti-CXCR7 antibody produced in rabbit;Anti-CXCR7, C-Terminal antibody produced in rabbit;Chemokine orphan receptor 1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![RDC1 Structure]() |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| WGK Germany | nwg | | Storage Class | 10 - Combustible liquids |
| Uses | Anti-PAR1 (Cleaved-Ser42), N-Terminal antibody produced in rabbit has been used in Western blotting. | | General Description | Anti-PAR1 (Cleaved-Ser42) Antibody detects endogenous levels of fragment of activated PAR1 (Cleaved-Ser42) protein.
Protease-activated receptor-1 (PAR1), also known as coagulation factor II thrombin receptor (F2R), is encoded by the gene mapped to human chromosome 5q13.3. The encoded protein is a cell surface seven-transmembrane G protein coupled receptor. | | Biochem/physiol Actions | Protease-activated receptor-1 (PAR1) facilitates angiogenesis and influences the process of tumor growth and disease progression. In addition, it also plays a vital role in inflammation and thrombosis. Mutation in the gene is associated with an increased risk of metastasis and poorer prognosis of renal cell carcinoma. Elevated expression of the gene has been observed in various types of cancers, such as ovarian, breast, lung, prostate cancer and melanoma. |
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