3'-(Trifluoromethyl)acetophenone

3'-(Trifluoromethyl)acetophenone Suppliers list

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3'-(Trifluoromethyl)acetophenone manufacturers

Asymmetric Catalysis and Biotransformation of 3'-(Trifluoromethyl)acetophenone for Chiral Synthesis
3'-(Trifluoromethyl)acetophenone undergoes asymmetric catalytic addition and biotransformation to synthesize chiral compounds ....
Jun 25，2025

3'-(Trifluoromethyl)acetophenone Basic information

Product Name:	3'-(Trifluoromethyl)acetophenone
Synonyms:	3'-(Trifluoromethyl)acetophenone,99%;3-Trifludromethylacetophen;1-[3-(Trifluoromethyl)phenyl]ethan-1-one, 3-Acetylbenzotrifluoride;3'-(TrifluoroMethyl)acetophenone, 97+%;1-[3-(Trifluoromethyl)phenyl]-1-ethanone;3-ACETYLBENZOTRIFLUORIDE;3-ACETYLBENZOFLUORIDE;3-(TRIFLUOROMETHYL)ACETOPHENONE
CAS:	349-76-8
MF:	C9H7F3O
MW:	188.15
EINECS:	206-490-4
Product Categories:	Building Blocks;C9;Chemical Synthesis;Ketones;Organic Building Blocks;Carbonyl Compounds;Aromatic Acetophenones & Derivatives (substituted);Organics;Benzene series;Multisubstituted Benzene;bc0001;OLED
Mol File:	349-76-8.mol

3'-(Trifluoromethyl)acetophenone Chemical Properties

Boiling point	198-200 °C(lit.)
density	1.235 g/mL at 25 °C(lit.)
vapor pressure	35Pa at 25℃
refractive index	n20/D 1.4611(lit.)
Fp	183 °F
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
color	Colorless to Red to Green
Specific Gravity	1.235
Water Solubility	620mg/L at 25℃
BRN	640151
InChI	1S/C9H7F3O/c1-6(13)7-3-2-4-8(5-7)9(10,11)12/h2-5H,1H3
InChIKey	ABXGMGUHGLQMAW-UHFFFAOYSA-N
SMILES	CC(=O)c1cccc(c1)C(F)(F)F
LogP	2.55 at 25℃
CAS DataBase Reference	349-76-8(CAS DataBase Reference)
NIST Chemistry Reference	3-CF3-C6H4-COCH3(349-76-8)
EPA Substance Registry System	Ethanone, 1-[3-(trifluoromethyl)phenyl]- (349-76-8)

Safety Information

MSDS Information

3'-(Trifluoromethyl)acetophenone Usage And Synthesis

Chemical Properties	CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID
Uses	3''-?(Trifluoromethyl)?acetophenone is a reagent used in the stabilization of endosomal-toll-like receptor TRL8 creating a sort of inhibitory activity.
General Description	Asymmetric catalytic addition of ethyl groups to 3′-(trifluoromethyl)acetophenone catalyzed by ligands derived from trans-1,2-diaminocyclohexane and camphor sulfonyl chloride has been reported. Phenylation of 3′-(trifluoromethyl)acetophenone in the presence of dihydroxy bis(sulfonamide) ligand (enantioselective catalyst), titanium tetraisopropoxide and diphenylzinc has been investigated.

3'-(Trifluoromethyl)acetophenone Preparation Products And Raw materials

Raw materials	3-Isopropylbenzotrifluoride-->Trifluoromethanesulfonic acid difluoromethyl ester-->3-Iodobenzotrifluoride-->PHENYL-2,2,2-TRIFLUOROETHYL-KETONE-->3-(Trifluoromethyl)phenylboronic acid-->3-(Trifluoromethyl)styrene-->ALPHA-METHYL-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL-->S-(Trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate-->3-Bromobenzotrifluoride
Preparation Products	3-(TRIFLUOROMETHYL)PHENACYL BROMIDE-->Ethanone, 2,2-dibromo-1-[3-(trifluoromethyl)phenyl]--->3-(Trifluoromethyl)benzoyl chloride-->3-OXO-3-(3-TRIFLUOROMETHYLPHENYL)PROPIONIC ACID ETHYL ESTER-->3-(TRIFLUOROMETHYL)PHENYLGLYOXAL HYDRATE-->N-Methyl-1-[3-(trifluoromethyl)phenyl]ethylamine-->Cinacalcet-->2,4-Imidazolidinedione, 5-methyl-5-[3-(trifluoromethyl)phenyl]--->Oxaflozane

Tag:3'-(Trifluoromethyl)acetophenone(349-76-8) Related Product Information

4-(TRIFLUOROMETHYL)PHENYLACETONITRILE 4'-(Trifluoromethoxy)acetophenone 3-(Trifluoromethyl)phenylacetone 3-Trifluoromethylphenol 2-(Trifluoromethyl)benzoic acid 3'-Methylacetophenone 3-Nitroacetophenone 3-(Trifluoromethyl)benzaldehyde 3-(Trifluoromethyl)benzoyl chloride Trifluoroacetophenone Trifluoromethanesulfonic acid Chalcone PHENYL VALERATE Acetophenone 3-(Trifluoromethyl)benzoic acid 4-Fluoroacetophenone 4'-(Trifluoromethyl)acetophenone 3-Aminoacetophenone

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