|
|
| | 3'-(Trifluoromethyl)acetophenone Basic information |
| | 3'-(Trifluoromethyl)acetophenone Chemical Properties |
| Boiling point | 198-200 °C(lit.) | | density | 1.235 g/mL at 25 °C(lit.) | | vapor pressure | 35Pa at 25℃ | | refractive index | n20/D 1.4611(lit.) | | Fp | 183 °F | | storage temp. | Sealed in dry,Room Temperature | | form | clear liquid | | color | Colorless to Red to Green | | Specific Gravity | 1.235 | | Water Solubility | 620mg/L at 25℃ | | BRN | 640151 | | InChI | 1S/C9H7F3O/c1-6(13)7-3-2-4-8(5-7)9(10,11)12/h2-5H,1H3 | | InChIKey | ABXGMGUHGLQMAW-UHFFFAOYSA-N | | SMILES | CC(=O)c1cccc(c1)C(F)(F)F | | LogP | 2.55 at 25℃ | | CAS DataBase Reference | 349-76-8(CAS DataBase Reference) | | NIST Chemistry Reference | 3-CF3-C6H4-COCH3(349-76-8) | | EPA Substance Registry System | Ethanone, 1-[3-(trifluoromethyl)phenyl]- (349-76-8) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 1 | | TSCA | TSCA listed | | HazardClass | IRRITANT | | HS Code | 29147090 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 3'-(Trifluoromethyl)acetophenone Usage And Synthesis |
| Chemical Properties | CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID | | Uses | 3''-(Trifluoromethyl)acetophenone is a reagent used in the stabilization of endosomal-toll-like receptor TRL8 creating a sort of inhibitory activity. | | General Description | Asymmetric catalytic addition of ethyl groups to 3′-(trifluoromethyl)acetophenone catalyzed by ligands derived from trans-1,2-diaminocyclohexane and camphor sulfonyl chloride has been reported. Phenylation of 3′-(trifluoromethyl)acetophenone in the presence of dihydroxy bis(sulfonamide) ligand (enantioselective catalyst), titanium tetraisopropoxide and diphenylzinc has been investigated. |
| | 3'-(Trifluoromethyl)acetophenone Preparation Products And Raw materials |
|