Isl-1

Isl-1 Suppliers list
Company Name: Shanghai Huzhen Industrial Co., LTD  
Tel: 021-60345367 13916550749
Email: sales@shzbio.com
Isl-1 Basic information
Product Name:Isl-1
Synonyms:ANTI-ISL1 antibody produced in mouse;ISL1;ISLET1;Isl-1
CAS:
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MW:0
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Product Categories:
Mol File:Mol File
Isl-1 Structure
Isl-1 Chemical Properties
storage temp. -20°C
form buffered aqueous solution
biological sourcemouse
Safety Information
Storage Class10 - Combustible liquids
MSDS Information
Isl-1 Usage And Synthesis
UsesThis gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. (provided by RefSeq)
Biological ActivityInsulin gene enhancer binding protein-1 (ISL-1) is a transcription factor which plays a vital role in the development of the heart, motor neurons and pancreas. It also stimulates adult pancreatic -cells proliferation. ISL1 might also be involved in the regulation of insulin expression. Elevated expression of the gene has been observed in patients with gastric cancer. Thus, the protein can be used as a potential biomarker and therapeutic target for gastric cancer. Mutation in the gene is associated with the increased risk of susceptibility to human congenital heart disease (CHD).
Isl-1 Preparation Products And Raw materials
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