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| | (SAR1,ILE4,8)-ANGIOTENSIN II Basic information |
| Product Name: | (SAR1,ILE4,8)-ANGIOTENSIN II | | Synonyms: | (SAR1,ILE4,8)-ANGIOTENSIN II;SAR-ARG-VAL-ILE-ILE-HIS-PRO-ILE-OH;SAR-ARG-VAL-ILE-ILE-HIS-PRO-ILE;REF DUPL: Sar-Arg-Val-Ile-Ile-His-Pro-Ile-OH;(Sar 1,Ile4·8)-Angiotensin II trifluoroacetate salt Sar-Arg-Val-Ile-Ile-His-Pro-Ile-OH trifluoroacetate salt;L-Isoleucine, N-methylglycyl-L-arginyl-L-valyl-L-isoleucyl-L-isoleucyl-L-histidyl-L-prolyl-;Octapeptide (NMe) G-RVIIHPI;(Sar 1,Ile4·8)-Angiotensin II trifluoroacetate salt | | CAS: | 185461-45-4 | | MF: | C43H75N13O9 | | MW: | 918.14 | | EINECS: | | | Product Categories: | | | Mol File: | 185461-45-4.mol |  |
| | (SAR1,ILE4,8)-ANGIOTENSIN II Chemical Properties |
| density | 1.34±0.1 g/cm3(Predicted) | | form | Solid | | pka | 3.72±0.22(Predicted) | | color | White to off-white | | Sequence | {Sar}-Arg-Val-Ile-Ile-His-Pro-Ile |
| | (SAR1,ILE4,8)-ANGIOTENSIN II Usage And Synthesis |
| Uses | (Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β[1]. | | IC 50 | Angiotensin II Type 1 | | References | [1] Sanni SJ, et al. [Sar1, Ile4, Ile8]-angiotensin II Potentiates Insulin Receptor Signalling and Glycogen Synthesis in Hepatocytes. Basic Clin Pharmacol Toxicol. 2018 May;122(5):460-469. DOI:10.1111/bcpt.12937 |
| | (SAR1,ILE4,8)-ANGIOTENSIN II Preparation Products And Raw materials |
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