3-beta-O-(cis-p-Coumaroyl)maslinic acid

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3-beta-O-(cis-p-Coumaroyl)maslinic acid Basic information
Product Name:3-beta-O-(cis-p-Coumaroyl)maslinic acid
Synonyms:3-beta-O-(cis-p-Coumaroyl)maslinic acid;(2alpha,3beta)-2-Hydroxy-3-[[(2Z)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-olean-12-en-28-oic acid;Olean-12-en-28-oic acid, 2-hydroxy-3-[[(2Z)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-, (2α,3β)-;3-O-cis-p-Coumaroylmaslinicacid/3β-O-(cis-p-Coumaroyl)maslinicacid
CAS:69297-40-1
MF:C39H54O6
MW:618.86
EINECS:
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Mol File:69297-40-1.mol
3-beta-O-(cis-p-Coumaroyl)maslinic acid Structure
3-beta-O-(cis-p-Coumaroyl)maslinic acid Chemical Properties
Melting point 278-282 °C
Boiling point 715.6±60.0 °C(Predicted)
density 1.20±0.1 g/cm3(Predicted)
pka4.62±0.70(Predicted)
Safety Information
MSDS Information
3-beta-O-(cis-p-Coumaroyl)maslinic acid Usage And Synthesis
Uses3-O-cis-p-Coumaroyl maslinic acid (compound 16) is a natural compound isolated from the ethyl acetate extract of leaves of Miconia albicans.3-O-cis-p-Coumaroyl maslinic acid can inhibit PTP1B, with the IC50 of 0.46 μM, and shows antimicrobial activity on Gram-positive bacteria and yeasts[1][2].
References[1] de Cássia Lemos Lima R, et al. High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans. Molecules. 2018;23(7):1755. DOI:10.3390/molecules23071755
[2] Braca A, et al. Antimicrobial triterpenoids from Licania heteromorpha. Planta Med. 2000;66(8):768-769. DOI:10.1055/s-2000-9601
3-beta-O-(cis-p-Coumaroyl)maslinic acid Preparation Products And Raw materials
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