2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid

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2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid manufacturers

  • SM4
  • SM4 pictures
  • $64.00
  • 2026-05-11
  • CAS:365542-77-4
  • Purity: 98.91%
  • Supply Ability: 10g
2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid Basic information
Product Name:2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid
Synonyms:2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid;2-Hydroxy-6-[2-(2-naphthyl)ethyl]benzoic acid;Benzoic acid, 2-hydroxy-6-[2-(2-naphthalenyl)ethyl]-;Sm4,Sm-4;2-Hydroxy-6-(2-(naphthalen-2-yl)ethyl)benzoic acid , Sm4
CAS:365542-77-4
MF:C19H16O3
MW:292.33
EINECS:
Product Categories:
Mol File:365542-77-4.mol
2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid Structure
2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid Chemical Properties
storage temp. 2-8°C
solubility DMSO: 2mg/mL, clear
form Solid
color Off-white to light brown
InChI1S/C19H16O3/c20-17-7-3-6-15(18(17)19(21)22)11-9-13-8-10-14-4-1-2-5-16(14)12-13/h1-8,10,12,20H,9,11H2,(H,21,22)
InChIKeyGGVFBUYNEPBFQT-UHFFFAOYSA-N
SMILESOC1=C(C(O)=O)C(CCC2=CC3=C(C=CC=C3)C=C2)=CC=C1
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid Usage And Synthesis
DescriptionSm4 is a novel SOX18 blocker, suppressing genes downstream of the gene for Sox18 and interferring with vascular development, showing anti-cancer and anti-metastatic effects.
UsesSm4 is a SOX18 inhibitor. Sm4 shows SOX18-DNA binding inhibitory activity. Sm4 selectively affects SOX18 transcriptional output in vitro. Sm4 blocks SoxF transcriptional activity in vivo. Sm4 can be used for cancer metastasis and vascular cancers research[1].
References[1] Mathias FRANCOIS. Inhibitors of sox18 protein activity for treating angiogenesis- and/or lymphangiogenesis-related diseases. Patent, WO2018112545A1.
2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid Preparation Products And Raw materials
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