- Benzyl-PEG5-N3
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2025-06-07
- CAS:86770-72-1
- Min. Order: 500mg
- Purity: >98.00%
- Supply Ability: 500mg
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| | Benzyl-PEG5-Azide Basic information |
| Product Name: | Benzyl-PEG5-Azide | | Synonyms: | Benzyl-PEG5-Azide;Bromoacetamido-PEG2-Azide;CAS_86770-72-1;BrCH2CONH-PEG2-N3;Benzyl-PEG4-N3;Benzyl-PEG5-N3;Benzyl-PEG4-azide;17-azido-1-phenyl-2,5,8,11,14-pentaoxaheptadecane | | CAS: | 86770-72-1 | | MF: | C17H27N3O5 | | MW: | 353.41338 | | EINECS: | | | Product Categories: | | | Mol File: | 86770-72-1.mol |  |
| | Benzyl-PEG5-Azide Chemical Properties |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| | Benzyl-PEG5-Azide Usage And Synthesis |
| Description | Bromoacetamido-PEG2-azide is a heterobifunctional PEG linker containing a reactive bromoacetamido and a terminal azide.The bromoacetamidogroup is a very reactive group for nucleophilic substitution. The azide group can react with alkyne, BCN, DBCO via Click Chemistry. | | Uses | Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Benzyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Benzyl-PEG5-Azide Preparation Products And Raw materials |
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