(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid

(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid Suppliers list

Company Name:	Shanghai Tachizaki Biomedical Research Center
Tel:	18014399201
Email:	sales@chemlab-tachizaki.com

Company Name:	Baoji Didu Pharmaceutical and Chemical Co., Ltd
Tel:	029-81145305 17791533577
Email:	1021@dideu.com

(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid Basic information

Product Name:	(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid
Synonyms:	(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid;2,4-Pyrrolidinedicarboxylic acid, 4-amino-1-(phenylmethyl)-, (2R,4R)-;(2R,4R)-4-amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid;1-Benzyl-APDC
CAS:	171336-76-8
MF:	C13H16N2O4
MW:	264.28
EINECS:
Product Categories:
Mol File:	171336-76-8.mol

(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid Chemical Properties

Safety Information

MSDS Information

(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid Usage And Synthesis

Uses	1-Benzyl-APDC acts as an agonist for mGluR6, with an EC50 of 20 μM in CHO cells. 1-Benzyl-APDC is a weak antagonist of mGluR2, with an IC50 of 200 μM[1].
IC 50	mGlu₆: 20 μM (EC₅₀); mGluR2: 200 μM (IC₅₀)
References	[1] J K Mukhopadhyaya, et al. Synthesis of N(1)-substituted analogues of (2R,4R)-4-amino-pyrrolidine-2,4-dicarboxylic acid as agonists, partial agonists, and antagonists of group II metabotropic glutamate receptors. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1919-24. DOI:10.1016/s0960-894x(01)00329-8

(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid Preparation Products And Raw materials

Tag:(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid(171336-76-8) Related Product Information

LY 341495 O-Phospho-L-serine N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide L-AP4 cinnabarinic acid MMPIP (hydrochloride)

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