- Ilexhainanoside D
-
- $0.00 / 5mg
-
2023-02-24
- CAS:1137648-52-2
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- Ilexhainanoside D
-
- $9.80 / 1KG
-
2020-02-11
- CAS:1137648-52-2
- Min. Order: 1g
- Purity: ＞98%
- Supply Ability: 20 tons
- Ilexhainanoside D
-
- $9.80 / 1KG
-
2020-02-11
- CAS:1137648-52-2
- Min. Order: 1g
- Purity: ＞98%
- Supply Ability: 20 tons
|
| | Ilexhainanoside D Basic information |
| Product Name: | Ilexhainanoside D | | Synonyms: | Ilexhainanoside D;Olean-12-ene-23,28-dioic acid, 3,19-dihydroxy-, 28-β-D-glucopyranosyl ester, (3β,4β,19α)- | | CAS: | 1137648-52-2 | | MF: | C36H56O11 | | MW: | 664.83 | | EINECS: | | | Product Categories: | | | Mol File: | 1137648-52-2.mol |  |
| | Ilexhainanoside D Chemical Properties |
| Boiling point | 788.1±60.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | pka | 4.47±0.70(Predicted) |
| | Ilexhainanoside D Usage And Synthesis |
| Uses | Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect[1]. | | in vivo | The combination of Ilexhainanoside D and Ilexsaponin A (60, 120 or 240?mg/kg; for 8 weeks) treatment significantly reduces the severity of non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet in a dose-dependent manner. The combination of Ilexhainanoside D and Ilexsaponin A treatment decreases the ratio of Firmicutes/Bacteroidetes, reduces the relative abundance of Desulfovibrio and increases the relative abundance of Akkermansia. The intestinal barrier is improved as evidenced by the upregulation of the expression of zonula occludens-1 (ZO-1) and occludin in the ileum. The combination of Ilexhainanoside D and Ilexsaponin A treatment reduces the entry of LPS into the circulation and decreases the hepatic gene expression levels of proinflammatory cytokines[1]. | | References | [1] Zhao W, et al. The combination of Ilexhainanoside D and ilexsaponin A1 reduces liver inflammation and improves intestinal barrier function in mice with high-fat diet-induced non-alcoholic fatty liver disease. Phytomedicine. 2019 Jul 26;63:153039. DOI:10.1016/j.phymed.2019.153039 |
| | Ilexhainanoside D Preparation Products And Raw materials |
|