| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:FEMA 4809 CAS:1374760-95-8 Purity:98% Package:100mg Remarks:S89745
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2-(4-METHYLPHENOXY)-N-(1H-PYRAZOL-3-YL)-N-(THIOPHEN-2-YLMETHYL)ACETAMIDE manufacturers
- FEMA-4809
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- $30.00 / 1mg
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2026-04-17
- CAS:1374760-95-8
- Min. Order:
- Purity: 99.90%
- Supply Ability: 10g
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| | 2-(4-METHYLPHENOXY)-N-(1H-PYRAZOL-3-YL)-N-(THIOPHEN-2-YLMETHYL)ACETAMIDE Basic information |
| | 2-(4-METHYLPHENOXY)-N-(1H-PYRAZOL-3-YL)-N-(THIOPHEN-2-YLMETHYL)ACETAMIDE Chemical Properties |
| Boiling point | 561.1±50.0 °C(Predicted) | | density | 1.323±0.06 g/cm3(Predicted) | | vapor pressure | 0.001Pa at 20℃ | | FEMA | 4809 | 2-(4-METHYLPHENOXY)-N-(1H-PYRAZOL-3-YL)-N-(THIOPHEN-2-YLMETHYL)ACETAMIDE | | storage temp. | Store at -20°C | | solubility | DMSO : 250 mg/mL (763.59 mM; Need ultrasonic) | | pka | 12.72±0.10(Predicted) | | form | Solid:particulate/powder | | color | Off-white to light yellow | | JECFA Number | 2237 | | Cosmetics Ingredients Functions | FRAGRANCE FLAVOURING ORAL CARE | | LogP | 2.4 at 22.7℃ and pH4-9 | | Surface tension | 69.5mN/m at 10.7mg/L and 20℃ |
| | 2-(4-METHYLPHENOXY)-N-(1H-PYRAZOL-3-YL)-N-(THIOPHEN-2-YLMETHYL)ACETAMIDE Usage And Synthesis |
| Uses | FEMA 4809 is a TRPM8 receptor agonist (EC50=0.2 nM) for use as a cooling agent. TRPM8 is the ion channel responsible for the cool perception[1]. | | References | [1] Alain Noncovich, et al. Discovery and development of a novel class of phenoxyacetyl amides as highly potent TRPM8 agonists for use as cooling agents. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3931-3938. DOI:10.1016/j.bmcl.2017.04.003 |
| | 2-(4-METHYLPHENOXY)-N-(1H-PYRAZOL-3-YL)-N-(THIOPHEN-2-YLMETHYL)ACETAMIDE Preparation Products And Raw materials |
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