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| | Hydroxybupropione Basic information |
| Product Name: | Hydroxybupropione | | Synonyms: | HYDROXYBUPROPION;HYDROXYBUPROPIONE;1-(3-CHLOROOPHENYL)-2-[(2-HYDROXY-1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE;2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE;1-(3-Chloroophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone, 2-Hydroxy-2-(3chlorophenyl)-3,5,5-trimethylmorpholine;1-(3-Chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one;1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone;(±)-Hydroxybupropion solution | | CAS: | 92264-81-8 | | MF: | C13H18ClNO2 | | MW: | 255.74 | | EINECS: | 200-835-2 | | Product Categories: | Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Bupropion | | Mol File: | 92264-81-8.mol |  |
| | Hydroxybupropione Chemical Properties |
| Melting point | 121-123°C | | Boiling point | 393.9±32.0 °C(Predicted) | | density | 1.150±0.06 g/cm3(Predicted) | | Fp | 2℃ | | storage temp. | -20°C | | solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) | | pka | 15.43±0.10(Predicted) | | form | Solid | | color | White to Pale Yellow | | Major Application | clinical testing | | InChI | 1S/C13H18ClNO2/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10/h4-7,9,15-16H,8H2,1-3H3 | | InChIKey | RCOBKSKAZMVBHT-UHFFFAOYSA-N | | SMILES | ClC1=CC(C2(O)C(C)NC(C)(C)CO2)=CC=C1 |
| Hazard Codes | F,Xn | | Risk Statements | 11-20/21/22-36 | | Safety Statements | 16-36/37 | | RIDADR | UN 1648 3 / PGII | | WGK Germany | 2 | | HS Code | 3822900000 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2 |
| | Hydroxybupropione Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | A metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3chlorophenyl)-355-trimethylmorpholine). See US Pat. # 6342496 | | Definition | ChEBI: Hydroxybupropion is an aromatic ketone. | | General Description | (±)-Hydroxybupropion is a primary metabolite of bupropion. Bupropion is a pharmaceutical used as an antidepressant and a smoking cessation drug sold under the trade names Wellbutrin and Zyban. This Certified Spiking Solution is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research. |
| | Hydroxybupropione Preparation Products And Raw materials |
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