ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
| 中文名称 | ASP-SER-PHE-VAL-GLY-LEU-MET-NH2 |
|---|---|
| 中文同义词 | 4-10-神经激肽 A;速激肽 NK2 受体激动剂多肽NEUROKININ A (4-10);神经激肽 A (4-10)、NEUROKININ A(4-10) |
| 英文名称 | NEUROKININ A (4-10) |
| 英文同义词 | NEUROKININ A (4-10);α-neurokinin fragment 4-10;DSFVGLM-NH2;H-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2;ASP-SER-PHE-VAL-GLY-LEU-MET-NH2;ALPHA-NEUROKININ FRAGMENT 4-10;L-Asp-L-Ser-L-Phe-L-Val-Gly-L-Leu-L-Met-NH2;NKA(4-10) |
| CAS号 | 97559-35-8 |
| 分子式 | C34H54N8O10S |
| 分子量 | 766.91 |
| EINECS号 | |
| 相关类别 | 生化试剂;多肽;其他生化试剂;标准品;Peptide;Agonist;Peptides for Cell Biology;Tachykinins |
| Mol文件 | 97559-35-8.mol |
| 结构式 |  |
ASP-SER-PHE-VAL-GLY-LEU-MET-NH2 性质
| 沸点 | 1231.2±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.276±0.06 g/cm3(Predicted) |
| 储存条件 | −20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 3.69±0.10(Predicted) |
| 形态 | 固体 |
| 序列 | Asp-Ser-Phe-Val-Gly-Leu-Met-NH2 |
Neurokinin A (4-10) 是速激肽 NK2 受体激动剂。
NK 2 receptor
Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK 2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK 2 receptor in human colon circular muscle. A high density of NK 2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding.
安全信息
| WGK Germany | 3 |
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| 提供商 | 语言 |
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英文
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