3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride

Request For Quotation
3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Suppliers list
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: Shanghai Standard Technology Co.,Ltd.  
Tel: 021-021-57127007-6622-6622 17621252073
Email: luzh@nature-standard.com
Company Name: Guangzhou Younan Technology Co., Ltd  
Tel: 020-82000279 18988941452
Email: YN_research@163.com
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840
Email: psaitong@jm-bio.com
Company Name: Shanghai Taopu Industrial Co., LTD  
Tel: 15900573766 18018507602
Email: 3165608826@qq.com
3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Basic information
Product Name:3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride
Synonyms:3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride;Columbamine chloride
CAS:1916-10-5
MF:C20H20ClNO4
MW:373.83
EINECS:
Product Categories:
Mol File:1916-10-5.mol
3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Structure
3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Chemical Properties
Melting point 239.5-240.5 °C
form Solid
color Light yellow to yellow
Major Applicationfood and beverages
pharmaceutical
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
MSDS Information
3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Usage And Synthesis
Usesfood and beverages
pharmaceutical
in vivo

Columbamine (5-20 mg/kg; 23 days) significantly decreases the tumor volumes in a dose-dependent manner in HCT116 xenograft mice model[4].

Animal Model:Six-weeks-old male BALB/c nude mice (subcutaneously injected with HCT116 and control cells on the opposite flanks of the same mouse)[4]
Dosage:5, 10, 20 mg/kg
Administration:Administered to experimental mice for 23 days
Result:Decreased the tumor volumes in a dose-dependent manner.
IC 50CYP3A4: 30.6 μM (IC50)
3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Preparation Products And Raw materials
Tag:3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride(1916-10-5) Related Product Information
Ruxolitinib 2-Deoxy-D-glucose ANGIOTENSIN II, HUMAN Carbonyl cyanide 3-chlorophenylhydrazone Metformin Anti-Aging Compound Library