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| | 2'-DEOXY-2'-FLUOROTHYMIDINE Basic information |
| Product Name: | 2'-DEOXY-2'-FLUOROTHYMIDINE | | Synonyms: | 1-(2'-DEOXY-2'-FLUORO-BETA-D-RIBOFURANOSYL)-5-METHYLURACIL;2,4(1H,3H)-PYRIMIDINENONE, 1(2-DEOXY-2-FLUORO-BETA-D-RIBOFURANOSYL)-5-METHYL;2'-DEOXY-2'-FLUORO-5-METHYLURIDINE;2'-DEOXY-2'-FLUOROTHYMIDINE;5-METHYL-2'-FLUORO-D-URIDINE;5-METHYL-2'-FLUOROURACIL;1-[(2R,3R,4R,5R)-3-FLUORO-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-METHYL-3H-PYRIMIDINE-2,4-DIONE;Uridine, 2'-deoxy-2'-fluoro-5-methyl- | | CAS: | 122799-38-6 | | MF: | C10H13FN2O5 | | MW: | 260.22 | | EINECS: | | | Product Categories: | Pyridines, Pyrimidines, Purines and Pteredines | | Mol File: | 122799-38-6.mol |  |
| | 2'-DEOXY-2'-FLUOROTHYMIDINE Chemical Properties |
| Melting point | 185-186 °C | | density | 1.55±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 9.55±0.10(Predicted) | | form | Solid | | color | White to off-white | | CAS DataBase Reference | 122799-38-6(CAS DataBase Reference) |
| | 2'-DEOXY-2'-FLUOROTHYMIDINE Usage And Synthesis |
| Chemical Properties | White to off-white powder | | Uses | 2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2)[1]. | | References | [1] Wiebe LI, et al. Biochemistry and biology of 2'-Fluoro-2'-deoxythymidine (FT), a putative highly selective substrate for thymidine kinase type 2 (TK2). Curr Radiopharm. 2012 Jan;5(1):38-46. DOI:10.2174/1874471011205010038 |
| | 2'-DEOXY-2'-FLUOROTHYMIDINE Preparation Products And Raw materials |
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