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| | 4-Chlorophenylacetic acid Basic information |
| | 4-Chlorophenylacetic acid Chemical Properties |
| Melting point | 102-105 °C(lit.) | | Boiling point | 241.44°C (rough estimate) | | density | 1.2315 (rough estimate) | | refractive index | 1.5660 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | ethanol: soluble100mg/mL, clear, faintly yellow | | pka | 4.19(at 25℃) | | form | Powder | | color | White to cream | | PH | 2.5-3 (100g/l, H2O, 20℃)suspension | | BRN | 1072816 | | InChI | InChI=1S/C8H7ClO2/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4H,5H2,(H,10,11) | | InChIKey | CDPKJZJVTHSESZ-UHFFFAOYSA-N | | SMILES | C1(CC(O)=O)=CC=C(Cl)C=C1 | | CAS DataBase Reference | 1878-66-6(CAS DataBase Reference) | | NIST Chemistry Reference | Acetic acid, p-chlorophenyl-(1878-66-6) | | EPA Substance Registry System | p-Chlorophenylacetic acid (1878-66-6) |
| Hazard Codes | Xn,Xi | | Risk Statements | 20/21-36/37/38 | | Safety Statements | 36/37-24/25-36-26 | | WGK Germany | 3 | | RTECS | AG0590000 | | F | 13 | | TSCA | TSCA listed | | HS Code | 29163900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Eye Irrit. 2
Skin Irrit. 2 | | Toxicity | mouse,LD50,intraperitoneal,1350mg/kg (1350mg/kg),Farmaco, Edizione Scientifica. Vol. 13, Pg. 286, 1958. |
| | 4-Chlorophenylacetic acid Usage And Synthesis |
| Chemical Properties | white to cream colored powder | | Uses | 4-Chlorophenylacetic Acid is a chlorinated phenyl acetic acid that is an antitumor differentiation inducer and may be an effective therapeutic agent in neuroblastoma therapy. 4-Chlorophenylacetic Acid shows plant growth-regulating activity. | | Uses | 4-Chlorophenylacetic acid was used to study the mechanism of aerobic degradation of 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane by Ralstonia eutropha A5. | | Definition | ChEBI: A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-chlorophenyl group. | | General Description | 4-Chlorophenylacetic acid possess anticancer properties. It is a novel therapeutic agent which can be useful in prevention or treatment of estrogen-sensitive breast cancer. It acts as carbon and energy supplement and is degraded by Pseudomonas sp. strain CBS3. | | Purification Methods | Purify it as for 3-chlorophenylacetic acid. [Beilstein 9 III 2263, 9 IV 1674.] |
| | 4-Chlorophenylacetic acid Preparation Products And Raw materials |
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