(5Z)-5-(2-oxo-1H-indol-3-ylidene)-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one

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(5Z)-5-(2-oxo-1H-indol-3-ylidene)-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one Basic information
Product Name:(5Z)-5-(2-oxo-1H-indol-3-ylidene)-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one
Synonyms:(5Z)-5-(2-oxo-1H-indol-3-ylidene)-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one;2H-Indol-2-one, 1,3-dihydro-3-[4-oxo-3-(2-propen-1-yl)-2-thioxo-5-thiazolidinylidene]-, (3Z)-;ClpB-IN-1;(Z)-3-Allyl-5-(2-oxoindolin-3-ylidene)-2-thioxothiazolidin-4-one
CAS:1453172-23-0
MF:C14H10N2O2S2
MW:302.37
EINECS:
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Mol File:1453172-23-0.mol
(5Z)-5-(2-oxo-1H-indol-3-ylidene)-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one Structure
(5Z)-5-(2-oxo-1H-indol-3-ylidene)-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one Chemical Properties
density 1.51±0.1 g/cm3(Predicted)
pka10.05±0.20(Predicted)
form Solid
color Brown to reddish brown
Safety Information
MSDS Information
(5Z)-5-(2-oxo-1H-indol-3-ylidene)-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one Usage And Synthesis
DescriptionMM01 is a novel broad-spectrum inflammasome inhibitor for the potential treatment of multifactorial diseases involving the dysregulation of multiple inflammasomes.
UsesClpB-IN-1 (compound 7) is a potent ClpB inhibitor. ClpB-IN-1 is a potential antibacterial agents[1].
References[1] Martin I, et, al. Screening and evaluation of small organic molecules as ClpB inhibitors and potential antimicrobials. J Med Chem. 2013 Sep 26;56(18):7177-89. DOI:10.1021/jm400499k
(5Z)-5-(2-oxo-1H-indol-3-ylidene)-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one Preparation Products And Raw materials
Tag:(5Z)-5-(2-oxo-1H-indol-3-ylidene)-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one(1453172-23-0) Related Product Information
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