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| | Acetyl PACAP (1-38) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt) Basic information |
| | Acetyl PACAP (1-38) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt) Chemical Properties |
| solubility | Water: 1 mg/ml |
| | Acetyl PACAP (1-38) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt) Usage And Synthesis |
| Description | Acetyl pituitary adenylate cyclase-activating peptide (PACAP) (1-38) is an N-terminally acetylated form of PACAP (1-38) (Item No. 24770).1 It binds to the PACAP receptor PAC1 (IC50 = 5.6 nM for the human receptor) and induces calcium mobilization and proliferation of PC12 cells (EC50s = 4.4 and 0.83 nM, respectively) with an efficacy comparable to PACAP (1-38). Acetyl PACAP (1-38) is resistant to degradation by dipeptidyl peptidase 4 (DPP-4) with a 10-fold longer half-life than PACAP (1-38), respectively.WARNING This product is not for human or veterinary use. | | References | [1] STEVE BOURGAULT . Novel stable PACAP analogs with potent activity towards the PAC1 receptor[J]. Peptides, 2008, 29 6: Pages 919-932. DOI: 10.1016/j.peptides.2008.01.022 |
| | Acetyl PACAP (1-38) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt) Preparation Products And Raw materials |
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